CDCA4 and ZNF451

Data Source:
BioGRID (two hybrid)

		CDCA4	ZNF451
Description		cell division cycle associated 4	zinc finger protein 451
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Plasma Membrane	Nucleus PML Body
	Molecular Function	Protein Binding Transcription Regulator Activity	Transcription Corepressor Activity Protein Binding Metal Ion Binding SUMO Ligase Activity
	Biological Process	Chromatin-mediated Maintenance Of Transcription	Regulation Of Gene Expression Protein Sumoylation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Histone H3-K9 Acetylation
Pathways
Drugs
Diseases
GWAS		Cerebrospinal fluid t-tau levels ( 29274321) Cerebrospinal fluid t-tau levels in normal cognition ( 29274321) Leukocyte telomere length ( 32109421)
Interacting Genes		25 interacting genes: BFSP2 C1orf109 DOK5 ENKD1 FAM222B FARS2 FNDC11 KAT2B KDM1A KLHL42 MKRN3 PARD6B PRMT6 SEPHS1 SHC3 SUOX SUPT7L SUV39H1 SUV39H2 TCAP TRIM28 TXN2 XPO1 YPEL3 ZNF451	33 interacting genes: AR CALCOCO2 CDC5L CDCA4 CPTP CREB1 CREBBP FAM118A FXR2 HTT JMJD6 KDM1A KLHL40 LZTR1 MID2 OPLAH PCBD1 PIAS1 PIAS2 PIK3R3 PML PRMT1 PRMT8 PRPF40A RAP1GDS1 RNF40 SNIP1 SUMO1 SUMO2 SUV39H1 UBC UBE2I ZNF467
Entrez ID		55038	26036
HPRD ID		13015	10332
Ensembl ID		ENSG00000170779	ENSG00000112200
Uniprot IDs		A0A024R6P3 Q9BXL8	B4DYS2 Q96JY2 Q9Y4E5
PDB IDs			5D2M
Enriched GO Terms of Interacting Partners?
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