HERC6 and HERC3

Data Source:
HPRD (in vivo)

		HERC6	HERC3
Description		HECT and RLD domain containing E3 ubiquitin protein ligase family member 6	HECT and RLD domain containing E3 ubiquitin protein ligase 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol	Cytosol Cytoplasmic Vesicle
	Molecular Function	Ubiquitin-protein Transferase Activity	Ubiquitin-protein Transferase Activity
	Biological Process	Protein Polyubiquitination	Protein Ubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Lean body mass ( 28552196) Metabolite levels ( 22916037) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Hair greying ( 26926045) Post bronchodilator FEV1/FVC ratio ( 26634245) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		4 interacting genes: HERC3 HERC4 NME2 UBE2L3	13 interacting genes: CCL22 CD33 HERC6 NME2 SRPK2 TK1 TRIM14 UBA52 UBC UBE2D1 UBE2L3 UBQLN1 UBQLN2
Entrez ID		55008	8916
HPRD ID		13647	16093
Ensembl ID		ENSG00000138642	ENSG00000138641
Uniprot IDs		Q8IVU3	B4DK41 Q15034
PDB IDs		5W87
Enriched GO Terms of Interacting Partners?
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