FAM118A and ATOX1

Data Source:
BioGRID (two hybrid)

		FAM118A	ATOX1
Description		family with sequence similarity 118 member A	antioxidant 1 copper chaperone
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Cytosol
	Molecular Function	Protein Binding Identical Protein Binding	Copper Ion Binding Protein Binding Metallochaperone Activity Copper Chaperone Activity Copper-dependent Protein Binding
	Biological Process		Copper Ion Transport Cellular Copper Ion Homeostasis Response To Oxidative Stress
Pathways			Detoxification of Reactive Oxygen Species Ion influx/efflux at host-pathogen interface
Drugs			Cisplatin Sucrose Benzamidine
Diseases
GWAS		Birth weight ( 31043758) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Chronotype ( 30696823) Dentures ( 31235808) Heel bone mineral density ( 30598549) Height ( 31562340) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Peanut allergy (maternal genetic effects) ( 29489655) Periventricular white matter hyperintensities ( 32517579)	Creatinine levels ( 29403010) Glomerular filtration rate ( 29403010) Red cell distribution width ( 32888494) Systolic blood pressure change trajectories ( 27980656)
Interacting Genes		14 interacting genes: AIDA ATOX1 CDC37 DCDC2 FAM118B GLRX3 LNX1 MOB1A MOB3C RNF4 SDCBP UBE2I WDR4 ZNF451	8 interacting genes: ATP7A ATP7B CFAP410 COMP FAM118A FKBP4 GGPS1 NECAB1
Entrez ID		55007	475
HPRD ID		07936	03779
Ensembl ID		ENSG00000100376	ENSG00000177556
Uniprot IDs		A0A024R4V3 Q9NWS6	O00244
PDB IDs			1FE0 1FE4 1FEE 1TL4 1TL5 2K1R 2LQ9 3CJK 3IWL 3IWX 4QOT 4YDX 4YEA 5F0W 5T7L
Enriched GO Terms of Interacting Partners?
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