ARFGAP3 and LIME1

Data Source:
BioGRID (two hybrid)

		ARFGAP3	LIME1
Description		ADP ribosylation factor GTPase activating protein 3	Lck interacting transmembrane adaptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Cytosol Membrane	Extracellular Space Integral Component Of Membrane B Cell Receptor Complex
	Molecular Function	GTPase Activator Activity Protein Binding Metal Ion Binding	Protein Binding Protein Kinase Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Secretion Vesicle-mediated Transport Positive Regulation Of GTPase Activity COPI Coating Of Golgi Vesicle	Adaptive Immune Response Regulation Of Transcription By RNA Polymerase II Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of MAP Kinase Activity T Cell Receptor Signaling Pathway B Cell Receptor Signaling Pathway Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of NIK/NF-kappaB Signaling
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Resting metabolic rate ( 28476931)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Crohn's disease ( 28067908) Estimated glomerular filtration rate ( 31015462) Inflammatory bowel disease ( 28067908 23128233) Meat-related diet ( 32066663) Prostate cancer ( 23535732) Refractive error ( 32231278) Ulcerative colitis ( 28067908)
Interacting Genes		8 interacting genes: APP CD14 CXCL8 LIME1 RTN4IP1 SMAD2 SYPL1 ZDHHC17	46 interacting genes: AGR3 AIG1 AQP1 ARFGAP3 BNIP2 C14orf180 CALN1 CIAO2A CLN6 EMD FRMD8 GAD2 GOSR2 GRB2 LCK LHFPL5 LPAR3 LYN MAN2B2 MEST MIEF2 NDRG4 NINJ1 PBX3 PKMYT1 PLCG2 PNPO PTPN9 RTP2 SEC22C SLC41A2 SNAP47 SNX1 STX6 STX7 TBRG4 TMBIM6 TMEM143 TMEM243 TMEM74 TMEM86B TMEM97 TRAF3IP3 UNC93B1 UPK2 ZFPL1
Entrez ID		26286	54923
HPRD ID		06444	07904
Ensembl ID		ENSG00000242247	ENSG00000203896
Uniprot IDs		A0A024R4U0 Q9NP61	A0A087WT39 Q9H400
PDB IDs		2CRW
Enriched GO Terms of Interacting Partners?
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