POP5 and RPP25

Data Source:
HPRD (in vitro)

		POP5	RPP25
Description		POP5 homolog, ribonuclease P/MRP subunit	ribonuclease P and MRP subunit p25
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GO Annotations	Cellular Component	Ribonuclease MRP Complex Nucleoplasm Nucleolar Ribonuclease P Complex Nucleolus Multimeric Ribonuclease P Complex	Ribonuclease MRP Complex Nucleoplasm Nucleolus Multimeric Ribonuclease P Complex Centriolar Satellite
	Molecular Function	Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	TRNA 5'-leader Removal RRNA Processing TRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	TRNA 5'-leader Removal RRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		tRNA processing in the nucleus	tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Chronotype ( 30696823) High light scatter reticulocyte count ( 27863252) Intake of total sugars ( 31005972)	Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes		17 interacting genes: CAMK2B CCDC102B CEP44 DCDC2 INCA1 KRT34 KRT40 NDUFAB1 POP1 POP4 REL RPP14 RPP25 RPP30 TRAF1 UBC USHBP1	22 interacting genes: ABI2 BACH2 BANP DDI1 HOMEZ KRT15 LDOC1 LRRC73 PDLIM7 PICK1 PNMA1 POP1 POP4 POP5 POP7 RBPMS RPP14 RPP38 SAT1 SF3B4 TERF2IP ZNF438
Entrez ID		51367	54913
HPRD ID		15158	15276
Ensembl ID		ENSG00000167272	ENSG00000178718
Uniprot IDs		Q969H6	Q9BUL9
PDB IDs		6AHR 6AHU	6AHR 6AHU 6CWX
Enriched GO Terms of Interacting Partners?
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