ESRP1 and MIRLET7B

Data Source:
BioGRID (unspecified method)

		ESRP1	MIRLET7B
Description		epithelial splicing regulatory protein 1	microRNA let-7b
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body Ribonucleoprotein Complex	Extracellular Space Extracellular Exosome Extracellular Vesicle
	Molecular Function	RNA Binding MRNA Binding Protein Binding	MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	MRNA Processing RNA Splicing Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Inner Ear Auditory Receptor Cell Fate Specification Regulation Of RNA Splicing	Negative Regulation Of Autophagy Cellular Response To Reactive Oxygen Species Gene Silencing By MiRNA Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Angiogenesis Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Pathways		Signaling by BRAF and RAF fusions FGFR2 alternative splicing
Drugs
Diseases
GWAS		Abstraction and mental flexibility ( 31596458) Urate levels ( 31578528)
Interacting Genes		45 interacting genes: ARID5A ATXN1 DAZAP2 KLHDC7B KRTAP19-5 MED25 MIR106A MIR106B MIR128-2 MIR138-1 MIR138-2 MIR141 MIR155 MIR15B MIR19B1 MIR19B2 MIR200A MIR200C MIR20B MIR21 MIR222 MIR25 MIR29C MIR34A MIR34B MIR363 MIR7-1 MIR9-1 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7F2 MIRLET7G MIRLET7I OXER1 PRR20A PRR20B PRR20C PRR20D PRR20E RBPMS2	99 interacting genes: ADARB1 AGO2 AIMP1 AIMP2 APOBEC3B ATXN2L C1QBP CELF1 CPSF1 CPSF6 CPSF7 CRTAP DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EIF2AK2 ELAVL1 EPRS1 ERAL1 ESRP1 FAM98A FIP1L1 FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 P3H1 PDCD11 PGAM5 PLOD1 PTBP1 PUF60 PUM2 PURA QARS1 RARS1 RBFOX2 RBM12B RBM14 RBM4 RBM4B RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SFPQ SPOUT1 SYMPK SYNCRIP TAF15 TENT2 TRA2A TRA2B TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346
Entrez ID		54845	406884
HPRD ID		07881
Ensembl ID		ENSG00000104413	ENSG00000284520
Uniprot IDs		A0A2U3TZN9 Q6NXG1
PDB IDs		2DHA 2RVJ
Enriched GO Terms of Interacting Partners?
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