ESRP1 and ARID5A

Data Source:
BioGRID (two hybrid)

		ESRP1	ARID5A
Description		epithelial splicing regulatory protein 1	AT-rich interaction domain 5A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body Ribonucleoprotein Complex	Nucleus Nucleoplasm Nucleolus
	Molecular Function	RNA Binding MRNA Binding Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding DNA Binding Transcription Corepressor Activity RNA Binding Protein Binding Transcription Factor Binding Estrogen Receptor Binding Identical Protein Binding Sequence-specific DNA Binding Retinoid X Receptor Binding Thyroid Hormone Receptor Binding Androgen Receptor Binding
	Biological Process	MRNA Processing RNA Splicing Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Inner Ear Auditory Receptor Cell Fate Specification Regulation Of RNA Splicing	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Innate Immune Response Negative Regulation Of Transcription, DNA-templated Cellular Response To Estrogen Stimulus
Pathways		Signaling by BRAF and RAF fusions FGFR2 alternative splicing
Drugs
Diseases
GWAS		Abstraction and mental flexibility ( 31596458) Urate levels ( 31578528)	Eosinophil counts ( 32888494 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Event-related brain oscillations ( 21184583)
Interacting Genes		45 interacting genes: ARID5A ATXN1 DAZAP2 KLHDC7B KRTAP19-5 MED25 MIR106A MIR106B MIR128-2 MIR138-1 MIR138-2 MIR141 MIR155 MIR15B MIR19B1 MIR19B2 MIR200A MIR200C MIR20B MIR21 MIR222 MIR25 MIR29C MIR34A MIR34B MIR363 MIR7-1 MIR9-1 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7F2 MIRLET7G MIRLET7I OXER1 PRR20A PRR20B PRR20C PRR20D PRR20E RBPMS2	127 interacting genes: ANKRD11 AR ATP6V0D2 ATXN1 ATXN1L BAG4 BAHD1 BANP BOLL C14orf119 C19orf54 CAMK2A CATSPER1 CCDC120 CCDC57 CKS1B COX5B CRYBA1 CRYBA2 CYSRT1 DAB1 DAZAP2 DOK6 DTX2 ESR2 ESRP1 FAM168B FHL3 FOXD2 FOXH1 GATA5 GLIS2 GOLGA2 GRB2 HDAC7 HOXA1 HSD3B7 INIP IRX6 KAZN KCTD9 KDF1 KRT40 KRTAP10-8 KRTAP12-2 KRTAP12-4 KRTAP15-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 KRTAP22-1 KRTAP26-1 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP8-1 LASP1 LENG8 LIMS3 LIMS4 LITAF LMO2 MAB21L2 MAGED1 MDFI MIEN1 MKRN3 MORN3 MYLIP NUDT22 ODAM OLIG3 OTX1 PHF1 PIBF1 PIN1 PITX1 PLA2G10 PLAGL2 PLEKHN1 PNMA1 POU1F1 PRDM6 PRKAB2 PRR20A PRR20B PRR20C PRR20D PRR20E QRICH1 RARA RBFOX1 RBPMS RBPMS2 RFC5 RHOXF2 RNF44 ROR2 RXRA SEC24A SH2D2A SMYD1 SOHLH1 SOX5 TEKT3 TEKT4 TENT5A TENT5D TGM7 THRA TNS2 TRAF1 TRIM27 TRIM73 TSC1 TSEN15 TSSK3 UBTD2 USP20 VAC14 VENTX ZC3H10 ZIC1 ZNF503 ZNF765
Entrez ID		54845	10865
HPRD ID		07881	12481
Ensembl ID		ENSG00000104413	ENSG00000196843
Uniprot IDs		A0A2U3TZN9 Q6NXG1	Q03989
PDB IDs		2DHA 2RVJ
Enriched GO Terms of Interacting Partners?
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