SLC6A20 and KRTAP10-1

Data Source:
BioGRID (two hybrid)

		SLC6A20	KRTAP10-1
Description		solute carrier family 6 member 20	keratin associated protein 10-1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane	Cytosol Keratin Filament
	Molecular Function	Proline:sodium Symporter Activity Protein Binding Amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transmembrane Transporter Activity L-isoleucine Transmembrane Transporter Activity L-proline Transmembrane Transporter Activity Amino-acid Betaine Transmembrane Transporter Activity
	Biological Process	Amino Acid Transport Glycine Transport Proline Transport Amino-acid Betaine Transport Sodium Ion Transmembrane Transport Amino Acid Import Across Plasma Membrane Transport Across Blood-brain Barrier L-isoleucine Import Across Plasma Membrane L-proline Import Across Plasma Membrane Proline Import Across Plasma Membrane	Keratinization
Pathways		Amino acid transport across the plasma membrane Na+/Cl- dependent neurotransmitter transporters Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG)	Keratinization
Drugs
Diseases		Iminoglycinuria
GWAS		Acne (severe) ( 24927181) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Hirschsprung disease ( 25310821) Immune reponse to smallpox (secreted TNF-alpha) ( 22610502) Macular thickness ( 30535121) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Severe COVID-19 infection with respiratory failure (analysis II) ( 32558485) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urinary metabolites ( 26352407 21572414)
Interacting Genes		11 interacting genes: ADAMTSL4 CYSRT1 KRTAP1-1 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 NBPF19 NOTCH2NLA	138 interacting genes: ADAMTSL4 AEN AMMECR1 ATP23 AVPI1 BAHD1 BCL6B C17orf50 C22orf39 CAMK1G CARD9 CATSPER1 CBX2 CHIC2 CHRD CLPP CRCT1 CREB5 CTSZ CXCL16 CYSRT1 DAAM2 DEFB112 DHX57 DKK1 DOCK2 ECE1 FAM76B FBXO34 FCHO1 FUCA2 GLRX3 HOXA1 HOXA9 HPCAL1 HSD3B7 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP12-1 KRTAP13-3 KRTAP2-3 KRTAP2-4 KRTAP21-2 KRTAP26-1 KRTAP3-2 KRTAP3-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP5-1 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LINGO1 MAPKBP1 MEOX2 MOBP MRPL12 NBPF19 NECTIN2 NKD1 NLK NOTCH2NLA NPDC1 NR1D2 NR4A1 NR4A3 NUFIP2 OTX1 PID1 PIN1 PLLP POM121L8P POU4F2 PPARA PRKAG1 PRM2 PRPF31 RNF8 RSPO2 SH3GLB2 SHFL SLC23A1 SLC6A20 SMCP SPATA24 SPATA3 SPATA8 SPRY1 SPRY2 TNP2 TRIM42 TSPAN4 TULP3 WT1 ZBTB24 ZNF101 ZNF124 ZNF138 ZNF264 ZNF286A ZNF329 ZNF417 ZNF433 ZNF438 ZNF439 ZNF440 ZNF559 ZNF572 ZNF581 ZNF587 ZNF625 ZNF664 ZNF768 ZNF785 ZSCAN12 ZSCAN26
Entrez ID		54716	386677
HPRD ID		16128	11184
Ensembl ID		ENSG00000163817	ENSG00000215455
Uniprot IDs		Q9NP91	P60331
PDB IDs
Enriched GO Terms of Interacting Partners?
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