SLC6A20

Description		solute carrier family 6 member 20
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane
	Molecular Function	Proline:sodium Symporter Activity Protein Binding Amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transmembrane Transporter Activity L-isoleucine Transmembrane Transporter Activity L-proline Transmembrane Transporter Activity Amino-acid Betaine Transmembrane Transporter Activity
	Biological Process	Amino Acid Transport Glycine Transport Proline Transport Amino-acid Betaine Transport Sodium Ion Transmembrane Transport Amino Acid Import Across Plasma Membrane Transport Across Blood-brain Barrier L-isoleucine Import Across Plasma Membrane L-proline Import Across Plasma Membrane Proline Import Across Plasma Membrane
Pathways		Amino acid transport across the plasma membrane Na+/Cl- dependent neurotransmitter transporters Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG)
Drugs
Diseases		Iminoglycinuria
GWAS		Acne (severe) ( 24927181) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Hirschsprung disease ( 25310821) Immune reponse to smallpox (secreted TNF-alpha) ( 22610502) Macular thickness ( 30535121) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Severe COVID-19 infection with respiratory failure (analysis II) ( 32558485) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urinary metabolites ( 26352407 21572414)
Interacting Genes		11 interacting genes: ADAMTSL4 CYSRT1 KRTAP1-1 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 NBPF19 NOTCH2NLA
Entrez ID		54716
HPRD ID		16128
Ensembl ID		ENSG00000163817
Uniprot IDs		Q9NP91
PDB IDs
Enriched GO Terms of Interacting Partners?
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