DDX49 and MIR15A

Data Source:
BioGRID (unspecified method)

		DDX49	MIR15A
Description		DEAD-box helicase 49	microRNA 15a
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Extracellular Space Extracellular Exosome Extracellular Vesicle
	Molecular Function	RNA Binding RNA Helicase Activity Protein Binding ATP Binding	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	RRNA Processing Positive Regulation Of Cell Growth Regulation Of RRNA Stability	Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cell Population Proliferation Negative Regulation Of Peptidyl-threonine Phosphorylation Negative Regulation Of Angiogenesis Negative Regulation Of NF-kappaB Transcription Factor Activity Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Positive Regulation Of Apoptotic Process Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Inflammatory Response Cellular Response To Glucose Stimulus Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration Negative Regulation Of Cell Chemotaxis To Fibroblast Growth Factor Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Endothelial Cell Apoptotic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Cerebrospinal fluid p-Tau181p:AB1-42 ratio ( 26252872) Cerebrospinal P-tau181p levels ( 26252872)
Interacting Genes		11 interacting genes: APP HAP1 MIR1-2 MIR138-2 MIR140 MIR15A MIR199A1 MIR214 PAGE1 PSMB2 STX1A	73 interacting genes: AIMP1 AIMP2 C1QBP CPSF1 DARS1 DDX1 DDX21 DDX3X DDX49 DHX36 DHX37 EIF2AK2 EPRS1 ERAL1 FAM98A FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT21 PDCD11 PGAM5 PLOD1 PRMT1 PTBP1 PUF60 QARS1 RARS1 RBM14 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SFPQ SPOUT1 SYNCRIP TAF15 TRA2A TRA2B TRIM71 TRMT10C UPF1 UTP20 YBX1 YBX3 ZNF346
Entrez ID		54555	406948
HPRD ID		10864
Ensembl ID		ENSG00000105671	ENSG00000283785
Uniprot IDs		Q9Y6V7
PDB IDs
Enriched GO Terms of Interacting Partners?
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