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DDX49 and MIR214
Data Source:
BioGRID
(unspecified method)
DDX49
MIR214
Description
DEAD-box helicase 49
microRNA 214
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleus
Perinuclear Region Of Cytoplasm
Extracellular Vesicle
Molecular Function
RNA Binding
RNA Helicase Activity
Protein Binding
ATP Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
RRNA Processing
Positive Regulation Of Cell Growth
Regulation Of RRNA Stability
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Lamellipodium Assembly
Negative Regulation Of Gene Expression
Negative Regulation Of Angiogenesis
Negative Regulation Of Cell Migration
Negative Regulation Of Actin Filament Polymerization
Gene Silencing By MiRNA
Negative Regulation Of Necroptotic Process
Cellular Response To Hypoxia
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration
Positive Regulation Of Vascular Associated Smooth Muscle Cell Dedifferentiation
Positive Regulation Of Connective Tissue Replacement
Pathways
rRNA modification in the nucleus and cytosol
Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS
Cerebrospinal fluid p-Tau181p:AB1-42 ratio (
26252872
)
Cerebrospinal P-tau181p levels (
26252872
)
Height (
31562340
)
Interacting Genes
11 interacting genes:
APP
HAP1
MIR1-2
MIR138-2
MIR140
MIR15A
MIR199A1
MIR214
PAGE1
PSMB2
STX1A
92 interacting genes:
AIMP1
AIMP2
AQR
ATXN2L
C1QBP
CDC5L
CELF1
CPSF1
DARS1
DDX1
DDX21
DDX23
DDX3X
DDX49
DHX36
DHX37
EDC4
EIF2AK2
EPRS1
ERAL1
FAM98A
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LRPPRC
MARS1
MATR3
MSI2
NOL6
NONO
NUDT21
NUFIP2
PDCD11
PGAM5
PLOD1
PTBP1
PTCD3
PUF60
PUM1
PUM2
QARS1
RARS1
RBFOX2
RBM10
RBM14
RBM4
RBM4B
RTCA
RTCB
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SFPQ
SPOUT1
STRBP
SUGP2
SYMPK
SYNCRIP
TAF15
TRA2A
TRA2B
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZC3H11A
ZFR
ZNF346
Entrez ID
54555
406996
HPRD ID
10864
Ensembl ID
ENSG00000105671
ENSG00000283844
Uniprot IDs
Q9Y6V7
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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