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NECAB2 and KANK2
Data Source:
BioGRID
(two hybrid)
NECAB2
KANK2
Description
N-terminal EF-hand calcium binding protein 2
KN motif and ankyrin repeat domains 2
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Plasma Membrane
Axon
Dendrite
Cytoplasm
Mitochondrion
Molecular Function
Calcium Ion Binding
Protein Binding
A2A Adenosine Receptor Binding
Type 5 Metabotropic Glutamate Receptor Binding
Protein Binding
Biological Process
Regulation Of Amyloid Precursor Protein Biosynthetic Process
Positive Regulation Of Adenosine Receptor Signaling Pathway
Positive Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Glutamate Receptor Signaling Pathway
Negative Regulation Of G Protein-coupled Receptor Internalization
Positive Regulation Of Protein Localization To Membrane
Negative Regulation Of Transcription By RNA Polymerase II
Apoptotic Process
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Regulation Of Rho Protein Signal Transduction
Negative Regulation Of Programmed Cell Death
Negative Regulation Of Vitamin D Receptor Signaling Pathway
Kidney Epithelium Development
Glomerular Visceral Epithelial Cell Migration
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS
Body mass index (change over time) (
25378290
)
Corneal astigmatism (
29422769
)
Response to platinum-based neoadjuvant chemotherapy in cervical cancer (
28120872
)
Rheumatoid arthritis (
30891314
)
Apolipoprotein B levels (
32203549
)
Cholesterol, total (
26780889
)
Coronary artery disease (
29212778
)
HDL cholesterol (
23505323
)
High light scatter reticulocyte count (
32888494
27863252
)
High light scatter reticulocyte percentage of red cells (
32888494
27863252
)
Immature fraction of reticulocytes (
32888494
27863252
)
Intraocular pressure (
31959993
)
Low density lipoprotein cholesterol levels (
32154731
)
Mean spheric corpuscular volume (
32888494
)
Red cell distribution width (
32888494
27863252
28957414
)
Reticulocyte count (
32888494
27863252
)
Reticulocyte fraction of red cells (
32888494
27863252
)
Triglyceride levels (
32203549
)
Interacting Genes
89 interacting genes:
ADORA2A
AIMP2
BEX2
BEX3
BYSL
C19orf25
C1orf109
C1orf216
CAGE1
CAPN3
CARD9
CCDC121
CCDC146
CCDC153
CCDC33
CCNK
CDC37
CENPO
CPEB2
DAXX
DFFA
DGCR6
DGCR6L
DTNBP1
DYNC1I2
EAF2
EHHADH
EIF4E2
EMILIN1
FAM161A
FAM161B
FANCG
FXR2
GCC1
GOLGA2
GTPBP10
HAUS1
INPP1
INTS10
ISCU
KANK2
KANSL1
KDM1A
KIFC3
KLC3
KLC4
KPNA2
LENG1
LNX1
MED14
MRPS27
MSGN1
MTMR9
MYO15B
MYPOP
NECAB1
NEK6
NIP7
NOC4L
NTAQ1
ODAD3
ODAD4
OIP5
PATJ
PCM1
PICK1
POLR2C
PRKAA2
PRPF18
PSMA1
PUS10
RCOR3
RIC8A
RUNX1T1
SDCBP
SH2D4A
SMARCD1
SNAPIN
SOGA1
SSC5D
TCEA2
TEX11
TRIM59
TRIML2
TTR
USHBP1
USP7
VTA1
ZNF655
185 interacting genes:
ABI3
AEN
ANKRD11
AP2B1
ARL14EP
ASB15
BEND7
BIRC7
BLZF1
BORCS6
C11orf1
C2orf68
CADPS
CAMK2G
CAPN3
CARD10
CARD9
CBX8
CCDC33
CCDC57
CCDC88B
CDC20B
CDC5L
CDKL3
CEACAM6
CEP55
CEP63
CEP70
CHCHD3
CHIC2
CINP
COG6
CRX
CSNK2A1
CUTC
CWF19L2
CYTH4
DDIT4L
DLGAP3
DPEP2NB
DTX2
DYNLL1
DYNLL2
EFHC2
EIF4E
ELOA
EXOSC8
FAM161A
FAM90A1
FHL2
FHL3
FKBP6
GADD45GIP1
GATA1
GEMIN4
GKAP1
GMCL1
GMNN
GOLGA2
GOLGA6A
GOLGA6L9
GPANK1
GPKOW
GPSM1
GRB10
HAND2
HOMER3
HSF2BP
HSPB2
HSPB2-C11orf52
IHO1
IKZF3
IL16
KIF9
KIFAP3
KIFC3
KRT27
KRT34
KRT40
KRT75
KRT86
KRTAP6-3
L3MBTL3
LBX1
LENG1
LHX1
LHX3
LMO1
LMO2
LMO3
LMO4
LZTS1
MAGEB4
MCCD1
MCRS1
MED19
MEOX1
MEOX2
MID2
MITD1
MKRN3
MOB1A
MOB3C
MORN3
MSS51
MTUS2
MYOZ3
NCOA1
NCOA5
NECAB2
NOS3
NUTM1
OIP5
PAX6
PCBD1
PDE9A
PDLIM7
PFDN6
PIBF1
PLAGL2
PLEKHA2
PNKP
PPP1CB
PRDM14
PRDM6
PRKAR1B
PRMT5
PRPF18
PRPF31
PRR5L
PSEN1
PSMB4
PSTPIP1
RAB11FIP2
RALBP1
RBCK1
RHOH
SCARA5
SCNM1
SERTAD3
SNAPIN
SNW1
SORBS3
SRPK2
STAC
SYT6
TAX1BP1
TEX11
TFIP11
TGM5
THAP1
THAP6
TIFA
TLE5
TOP3B
TRAF1
TRAF2
TRAF4
TRIB3
TRIM35
TRIM54
TSGA10
TSGA10IP
TSPYL6
TXLNA
UBAP2
USHBP1
UTP14C
VMAC
VPS52
VWC2
WASF3
WASHC1
ZBTB42
ZFP57
ZMAT2
ZMYND12
ZNF212
ZNF414
ZNF512
ZNF648
ZNF774
ZNF784
ZNHIT1
ZRANB1
Entrez ID
54550
25959
HPRD ID
13263
12463
Ensembl ID
ENSG00000103154
ENSG00000197256
Uniprot IDs
Q7Z6G3
Q63ZY3
PDB IDs
4HBD
5YBV
Enriched GO Terms of Interacting Partners
?
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Tagcloud (Difference)
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Tagcloud (Intersection)
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