KRT20 and PRC1

Data Source:
HPRD (two hybrid)

		KRT20	PRC1
Description		keratin 20	protein regulator of cytokinesis 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Intermediate Filament	Spindle Pole Nucleus Nucleoplasm Chromosome Cytoplasm Spindle Cytosol Spindle Microtubule Plasma Membrane Microtubule Cytoskeleton Midbody Intercellular Bridge Contractile Ring Mitotic Spindle Midzone
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding	Protein Binding Microtubule Binding Kinesin Binding Protein Kinase Binding
	Biological Process	Apoptotic Process Cellular Response To Starvation Keratinization Intermediate Filament Organization Regulation Of Protein Secretion Cornification	Mitotic Spindle Elongation Microtubule Cytoskeleton Organization Microtubule Bundle Formation Positive Regulation Of Cell Population Proliferation Regulation Of Cytokinesis Mitotic Spindle Midzone Assembly Cell Division
Pathways		Keratinization Formation of the cornified envelope	RHO GTPases activate CIT
Drugs
Diseases
GWAS		Height ( 19893584)	Breast cancer ( 29059683 25038754) Mean platelet volume ( 32888494 27863252) Multisite chronic pain ( 31194737) Red cell distribution width ( 32888494) Type 2 diabetes ( 22885922 24509480 30054458 30297969 26818947 32499647 20581827 30718926 28869590)
Interacting Genes		46 interacting genes: ABI2 AMOTL2 ANKRD36BP1 BBLN BCAS2 CCDC196 CCDC85B COASY CYSRT1 DES EIF4E2 EXOC8 FXR2 KRT13 KRT15 KRT24 KRT27 KRT3 KRT31 KRT34 KRT40 KRT72 KRT75 KRT76 KRT80 KRTAP1-1 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP6-3 NOTCH2NLA NUP62 PIK3R2 PLEKHA5 PPP1R13B PRC1 PRPH SNAPIN TFIP11 TXLNA USHBP1 VIM WASHC1 ZC2HC1C ZC3H14	29 interacting genes: AKAP9 CASK CCDC85B CCNA2 CCNB1 CCNE1 CDK1 CDK2 CINP FXR2 KIF3B KIF4A KLC2 KLC4 KRT20 MAT2A NDEL1 PCM1 PKIA PLK1 RACGAP1 RBM10 RPA2 SF3B2 SLAIN1 SUMO2 TRIM37 USHBP1 YWHAE
Entrez ID		54474	9055
HPRD ID		12193	17899
Ensembl ID		ENSG00000171431	ENSG00000198901
Uniprot IDs		P35900	A0A024RC67 O43663
PDB IDs			3NRX 3NRY 4L3I 4L6Y 5KMG
Enriched GO Terms of Interacting Partners?
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