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TOLLIP and IL1RAP
Data Source:
HPRD
(in vivo, two hybrid)
TOLLIP
IL1RAP
Description
toll interacting protein
interleukin 1 receptor accessory protein
Image
GO Annotations
Cellular Component
Extracellular Region
Cytoplasm
Cytosol
Nuclear Body
Protein-containing Complex
Azurophil Granule Lumen
Specific Granule Lumen
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Extracellular Region
Plasma Membrane
Integral Component Of Plasma Membrane
Membrane
Glutamatergic Synapse
Molecular Function
Interleukin-1, Type I Receptor Binding
Protein Binding
Kinase Binding
Ubiquitin Conjugating Enzyme Binding
Ubiquitin Protein Ligase Binding
SUMO Binding
Toll-like Receptor Binding
Ubiquitin Binding
Interleukin-33 Receptor Activity
Interleukin-1 Receptor Activity
Interleukin-1 Receptor Binding
NAD(P)+ Nucleosidase Activity
NAD+ Nucleotidase, Cyclic ADP-ribose Generating
Biological Process
Ubiquitin-dependent Protein Catabolic Process
Autophagy
Inflammatory Response
Signal Transduction
Phosphorylation
Epithelial Cell Differentiation
Positive Regulation Of Protein Sumoylation
Protein Localization To Endosome
Neutrophil Degranulation
Innate Immune Response
Leukocyte Activation
Interleukin-1-mediated Signaling Pathway
Inflammatory Response
Immune Response
Cytokine-mediated Signaling Pathway
Positive Regulation Of Interleukin-13 Production
Positive Regulation Of Interleukin-5 Production
Positive Regulation Of Interleukin-6 Production
Interleukin-33-mediated Signaling Pathway
Innate Immune Response
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Synapse Assembly
Protein-containing Complex Assembly
Interleukin-1-mediated Signaling Pathway
Regulation Of Postsynaptic Density Assembly
Trans-synaptic Signaling By Trans-synaptic Complex
Synaptic Membrane Adhesion
Regulation Of Presynapse Assembly
Pathways
Neutrophil degranulation
Interleukin-1 signaling
Drugs
Diseases
GWAS
Gout (
32238385
)
Idiopathic pulmonary fibrosis (
24429156
)
Blood protein levels (
30072576
29875488
28240269
)
Longitudinal change in brain amyloid plaque burden (
26268530
)
Lung cancer (
18385676
)
Waist circumference (
20966902
)
Interacting Genes
78 interacting genes:
ACTN2
ARRDC3
ATXN1
BHLHE40
C19orf54
CDIP1
CHD6
CPSF6
CSN1S1
CSN2
CSTF1
DAB1
DAZAP2
DCDC2
DDIT4L
DZIP3
EIF2AK2
FAM166B
FAM168A
FTH1
GGA1
GGA2
GGA3
GUCD1
HERPUD1
IL1R1
IL1RAP
IRAK1
IRAK2
KRTAP13-3
KRTAP15-1
KRTAP19-7
KRTAP6-1
KRTAP6-2
KRTAP7-1
LDB1
MEDAG
MSS51
MSX2
MVP
N4BP2
NRF1
NTAQ1
ODAM
PEG10
PHAF1
PRPF39
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PSMB1
RBFOX1
RBFOX2
RBPMS
RHOXF2
SEPTIN1
SETDB1
SIAH1
STN1
TBX3
TENT5A
TLR2
TLR4
TOM1
TOM1L1
TOM1L2
TTC9C
UBC
USP54
WBP2
WRNIP1
XRN2
ZBTB16
ZHX1
ZMYND19
ZRANB1
20 interacting genes:
CCNI
IL18R1
IL1A
IL1B
IL1R1
IL1R2
IRAK1
KPNA1
MARCHF8
MC4R
MYD88
PIK3R1
PRKCI
PRPF40A
PTPRD
RAC1
SIRPA
STAT3
TICAM2
TOLLIP
Entrez ID
54472
3556
HPRD ID
05887
04021
Ensembl ID
ENSG00000078902
ENSG00000196083
Uniprot IDs
B3KR28
E9PNS3
F2Z2Y8
Q6FIE9
Q8N8J5
Q9H0E2
A8K6K4
Q9NPH3
PDB IDs
1WGL
2N31
3O4O
4DEP
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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