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POLR2C and TAF15
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vivo)
POLR2C
TAF15
Description
RNA polymerase II subunit C
TATA-box binding protein associated factor 15
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
RNA Polymerase II, Core Complex
Cytosol
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Molecular Function
DNA Binding
DNA-directed 5'-3' RNA Polymerase Activity
Protein Binding
Protein Dimerization Activity
DNA Binding
Transcription Coregulator Activity
RNA Binding
Protein Binding
Metal Ion Binding
Biological Process
MRNA Splicing, Via Spliceosome
Transcription-coupled Nucleotide-excision Repair
Transcription, DNA-templated
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Fibroblast Growth Factor Receptor Signaling Pathway
RNA Metabolic Process
Somatic Stem Cell Population Maintenance
SnRNA Transcription By RNA Polymerase II
Positive Regulation Of Viral Transcription
Regulation Of Gene Silencing By MiRNA
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Positive Regulation Of Transcription, DNA-templated
MRNA Stabilization
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Viral Messenger RNA Synthesis
MicroRNA (miRNA) biogenesis
Transcriptional regulation by small RNAs
PIWI-interacting RNA (piRNA) biogenesis
Activation of anterior HOX genes in hindbrain development during early embryogenesis
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Signaling by FGFR2 IIIa TM
Estrogen-dependent gene expression
Inhibition of DNA recombination at telomere
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
RNA Polymerase II Pre-transcription Events
Regulation of TP53 Activity through Phosphorylation
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
Extraskeletal myxoid chondrosarcoma
GWAS
Blood protein levels (
28240269
)
Reticulocyte count (
27863252
)
Reticulocyte fraction of red cells (
27863252
)
Interacting Genes
29 interacting genes:
ATF4
ATF7IP
C11orf58
CCHCR1
EEF1A1
ERG28
ITCH
LRIF1
MYOG
NECAB2
NEDD4
NFKBIA
NUDT21
OTUD5
POLR2A
POLR2B
POLR2D
POLR2E
POLR2F
POLR2G
POLR2H
POLR2J
POLR2K
POLR2L
SMARCC2
STC2
TAF15
UBC
UBE2W
93 interacting genes:
ARID1A
CACNA1A
H2AC20
H3-4
H3C1
H4C14
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
POLR2C
POLR2E
POLR2G
SAFB
SF1
SMARCA4
SMARCC1
SMARCC2
TAF1
TAF12
TAF13
TAF5
TAF7
YWHAG
ZNF384
Entrez ID
5432
8148
HPRD ID
15945
09031
Ensembl ID
ENSG00000102978
ENSG00000270647
Uniprot IDs
P19387
Q6FGR6
Q92804
PDB IDs
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
6DRD
6O9L
2MMY
Enriched GO Terms of Interacting Partners
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