TAF15 and MIR29A

Data Source:
BioGRID (unspecified method)

		TAF15	MIR29A
Description		TATA-box binding protein associated factor 15	microRNA 29a
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm	Extracellular Space Cytoplasm Mitochondrion Extracellular Exosome Extracellular Vesicle
	Molecular Function	DNA Binding Transcription Coregulator Activity RNA Binding Protein Binding Metal Ion Binding	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated MRNA Stabilization Regulation Of Signal Transduction By P53 Class Mediator	Negative Regulation Of Cell Population Proliferation Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Angiogenesis Positive Regulation Of Cell Migration Negative Regulation Of Cell Migration Negative Regulation Of Collagen Biosynthetic Process Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Positive Regulation Of Apoptotic Process Regulation Of DNA Methylation Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Angiogenesis Positive Regulation Of Protein Kinase B Signaling Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of Circulating Fibrinogen Levels Positive Regulation Of Wound Healing Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Negative Regulation Of Amyloid-beta Formation Negative Regulation Of Amyloid Precursor Protein Catabolic Process Positive Regulation Of Vascular Endothelial Cell Proliferation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases		Extraskeletal myxoid chondrosarcoma
GWAS		Blood protein levels ( 28240269) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)	Basal cell carcinoma ( 31174203) HDL cholesterol levels ( 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Keratinocyte cancer (MTAG) ( 31174203) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Neutrophil count ( 32888494) Pancreatic cancer ( 25086665) Red blood cell count ( 32888494) Triglyceride levels ( 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) White blood cell count ( 32888494)
Interacting Genes		93 interacting genes: ARID1A CACNA1A H2AC20 H3-4 H3C1 H4C14 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I POLR2C POLR2E POLR2G SAFB SF1 SMARCA4 SMARCC1 SMARCC2 TAF1 TAF12 TAF13 TAF5 TAF7 YWHAG ZNF384	84 interacting genes: AIMP2 APOBEC3B AQR C1QBP CPSF1 CPSF6 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 FAM98A FUS HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 NOL6 NONO NUDT21 PDCD11 PRMT1 PTBP1 PTBP3 PUF60 PUM1 RARS1 RBFOX2 RBM14 RBM4 RBM45 RBM47 RBMS1 RBMS2 RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TENT2 TIAL1 TRA2B TRIM25 TRIM71 UPF1 USP36 UTP20 YBX1 YBX3 ZC3H7A ZC3H7B ZNF346
Entrez ID		8148	407021
HPRD ID		09031
Ensembl ID		ENSG00000270647	ENSG00000284032
Uniprot IDs		Q92804
PDB IDs		2MMY
Enriched GO Terms of Interacting Partners?
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