PODXL and SLC9A3R2

Data Source:
HPRD (in vitro, in vivo)

		PODXL	SLC9A3R2
Description		podocalyxin like	SLC9A3 regulator 2
Image		No pdb structure
GO Annotations	Cellular Component	Ruffle Extracellular Space Nucleolus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane Lamellipodium Filopodium Microvillus Membrane Centriolar Satellite Slit Diaphragm Intracellular Membrane-bounded Organelle Membrane Raft Extracellular Exosome	Nucleus Plasma Membrane Focal Adhesion Endomembrane System Apical Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Signaling Receptor Binding Protein Binding Beta-catenin Binding Protein C-terminus Binding Phosphatase Binding Type 2 Metabotropic Glutamate Receptor Binding Type 3 Metabotropic Glutamate Receptor Binding Identical Protein Binding Protein-membrane Adaptor Activity Cadherin Binding
	Biological Process	Cell Adhesion Negative Regulation Of Cell Adhesion Cell Migration Negative Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Migration Regulation Of Microvillus Assembly Positive Regulation Of Cell-cell Adhesion Mediated By Integrin Glomerular Visceral Epithelial Cell Development Epithelial Tube Formation	Protein-containing Complex Assembly Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Alcohol dependence symptom count ( 27151647) Diastolic blood pressure ( 27841878) Hypertension ( 28273873) Idiopathic dilated cardiomyopathy ( 29495422) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Pulse pressure ( 30578418) Schizophrenia ( 25056061) Systolic blood pressure ( 27841878 30578418)	Diastolic blood pressure ( 27841878 30578418) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) Platelet distribution width ( 32888494) Pulse pressure ( 30578418) Red blood cell count ( 32888494) Reticulocyte count ( 32888494) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		4 interacting genes: SELL SGTB SLC9A3R2 UBQLN2	41 interacting genes: ABCC4 ACTN4 ADORA2B ADRB2 ATP2B2 CFTR DLGAP4 EZR KCNJ1 LPAR1 LPAR2 P2RY1 PDGFRB PDPK1 PDZK1 PLCB3 PODXL PRKACA PRKCA PTEN PTH1R RDX RPS6KA1 SGK1 SGK3 SIAH1 SLC13A1 SLC22A4 SLC22A5 SLC22A9 SLC26A3 SLC34A1 SLC9A3 SLCO1A2 SLCO3A1 SRY TAZ TBC1D10A TRAF4 WWP2 WWTR1
Entrez ID		5420	9351
HPRD ID		04025	05946
Ensembl ID		ENSG00000128567	ENSG00000065054
Uniprot IDs		O00592 Q96N83	Q15599
PDB IDs			2D11 2HE4 2OCS 4P0C
Enriched GO Terms of Interacting Partners?
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