SLC9A3R2 and ABCC4

Data Source:
BioGRID (pull down)

		SLC9A3R2	ABCC4
Description		SLC9A3 regulator 2	ATP binding cassette subfamily C member 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Focal Adhesion Endomembrane System Apical Plasma Membrane Extracellular Exosome	Plasma Membrane Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Platelet Dense Granule Membrane External Side Of Apical Plasma Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding Beta-catenin Binding Protein C-terminus Binding Phosphatase Binding Type 2 Metabotropic Glutamate Receptor Binding Type 3 Metabotropic Glutamate Receptor Binding Identical Protein Binding Protein-membrane Adaptor Activity Cadherin Binding	Protein Binding ATP Binding Purine Nucleotide Transmembrane Transporter Activity ABC-type Glutathione S-conjugate Transporter Activity Efflux Transmembrane Transporter Activity Ion Transmembrane Transporter Activity, Phosphorylative Mechanism 15-hydroxyprostaglandin Dehydrogenase (NAD+) Activity ATPase Activity ATPase-coupled Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity
	Biological Process	Protein-containing Complex Assembly Protein Localization To Plasma Membrane	Platelet Degranulation Response To Organonitrogen Compound Response To Organic Cyclic Compound Prostaglandin Secretion Bile Acid Signaling Pathway Response To Drug Xenobiotic Transport Positive Regulation Of Smooth Muscle Cell Proliferation Transmembrane Transport Cilium Assembly CAMP Transport Leukotriene Transport Anion Transmembrane Transport Export Across Plasma Membrane Transport Across Blood-brain Barrier
Pathways			Platelet degranulation ABC-family proteins mediated transport
Drugs			ATP
Diseases
GWAS		Diastolic blood pressure ( 27841878 30578418) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) Platelet distribution width ( 32888494) Pulse pressure ( 30578418) Red blood cell count ( 32888494) Reticulocyte count ( 32888494) Systolic blood pressure ( 27841878 30578418)	Acute post-radiotherapy pain in breast cancer ( 31196165) Airway responsiveness in chronic obstructive pulmonary disease ( 25514360) Blood metabolite levels ( 24816252) Breast cancer ( 17903305) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Longevity ( 20834067) Parent of origin effect on language impairment (paternal) ( 24571439) Platelet count ( 22139419 29403010 32888494 27863252) Plateletcrit ( 32888494 27863252) Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer ( 23478653)
Interacting Genes		41 interacting genes: ABCC4 ACTN4 ADORA2B ADRB2 ATP2B2 CFTR DLGAP4 EZR KCNJ1 LPAR1 LPAR2 P2RY1 PDGFRB PDPK1 PDZK1 PLCB3 PODXL PRKACA PRKCA PTEN PTH1R RDX RPS6KA1 SGK1 SGK3 SIAH1 SLC13A1 SLC22A4 SLC22A5 SLC22A9 SLC26A3 SLC34A1 SLC9A3 SLCO1A2 SLCO3A1 SRY TAZ TBC1D10A TRAF4 WWP2 WWTR1	6 interacting genes: ERBIN MPP1 PDZK1 SLC9A3R1 SLC9A3R2 SNTA1
Entrez ID		9351	10257
HPRD ID		05946	05583
Ensembl ID		ENSG00000065054	ENSG00000125257
Uniprot IDs		Q15599	A8K2Q2 O15439
PDB IDs		2D11 2HE4 2OCS 4P0C
Enriched GO Terms of Interacting Partners?
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