SLC9A3R2 and LPAR2

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		SLC9A3R2	LPAR2
Description		SLC9A3 regulator 2	lysophosphatidic acid receptor 2
Image
GO Annotations	Cellular Component	Nucleus Plasma Membrane Focal Adhesion Endomembrane System Apical Plasma Membrane Extracellular Exosome	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Endocytic Vesicle
	Molecular Function	Signaling Receptor Binding Protein Binding Beta-catenin Binding Protein C-terminus Binding Phosphatase Binding Type 2 Metabotropic Glutamate Receptor Binding Type 3 Metabotropic Glutamate Receptor Binding Identical Protein Binding Protein-membrane Adaptor Activity Cadherin Binding	G Protein-coupled Receptor Activity Protein Binding Lipid Binding Lysophosphatidic Acid Receptor Activity
	Biological Process	Protein-containing Complex Assembly Protein Localization To Plasma Membrane	G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Phospholipase C Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Metabolic Process
Pathways			G alpha (q) signalling events G alpha (i) signalling events Lysosphingolipid and LPA receptors
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878 30578418) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) Platelet distribution width ( 32888494) Pulse pressure ( 30578418) Red blood cell count ( 32888494) Reticulocyte count ( 32888494) Systolic blood pressure ( 27841878 30578418)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Schizophrenia ( 23974872) Sphingolipid levels ( 22359512)
Interacting Genes		41 interacting genes: ABCC4 ACTN4 ADORA2B ADRB2 ATP2B2 CFTR DLGAP4 EZR KCNJ1 LPAR1 LPAR2 P2RY1 PDGFRB PDPK1 PDZK1 PLCB3 PODXL PRKACA PRKCA PTEN PTH1R RDX RPS6KA1 SGK1 SGK3 SIAH1 SLC13A1 SLC22A4 SLC22A5 SLC22A9 SLC26A3 SLC34A1 SLC9A3 SLCO1A2 SLCO3A1 SRY TAZ TBC1D10A TRAF4 WWP2 WWTR1	7 interacting genes: ARHGEF11 ARHGEF12 ATXN1 GIPC1 SLC9A3R1 SLC9A3R2 TRIP6
Entrez ID		9351	9170
HPRD ID		05946	05487
Ensembl ID		ENSG00000065054	ENSG00000064547
Uniprot IDs		Q15599	A0A024R7M9 Q9HBW0
PDB IDs		2D11 2HE4 2OCS 4P0C	4P0C
Enriched GO Terms of Interacting Partners?
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