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TRIM34 and UBE2K
Data Source:
BioGRID
(two hybrid)
TRIM34
UBE2K
Description
tripartite motif containing 34
ubiquitin conjugating enzyme E2 K
Image
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytosol
Nucleus
Cytosol
Filopodium Tip
Molecular Function
Molecular_function
Zinc Ion Binding
Protein Kinase Binding
Identical Protein Binding
Protein Homodimerization Activity
Ubiquitin Protein Ligase Activity
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ubiquitin Protein Ligase Binding
Ubiquitin-ubiquitin Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Biological Process
Protein Polyubiquitination
Regulation Of Gene Expression
Positive Regulation Of Autophagy
Protein Ubiquitination
Regulation Of Protein Localization
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Innate Immune Response
Regulation Of Viral Entry Into Host Cell
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Defense Response To Virus
Interferon-gamma-mediated Signaling Pathway
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Peptidyl-threonine Phosphorylation
Free Ubiquitin Chain Polymerization
Protein Ubiquitination
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Interferon-beta
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Type I Interferon-mediated Signaling Pathway
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Protein K48-linked Ubiquitination
Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Pathways
Interferon gamma signaling
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Negative regulators of DDX58/IFIH1 signaling
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Malaria (
31844061
)
Mean corpuscular hemoglobin concentration (
32888494
)
Red blood cell count (
32888494
)
Apolipoprotein A1 levels (
32203549
)
HDL cholesterol levels (
32203549
)
Plasma amyloid beta peptide concentrations (ABx-40) (
24535457
)
Platelet count (
32888494
)
Interacting Genes
7 interacting genes:
BIRC2
MKRN3
MNAT1
TRIM5
UBE2K
UBE2U
USP2
95 interacting genes:
AMFR
ANAPC11
BARD1
BFAR
BIRC7
BIRC8
BRCA1
CASP12
CBLC
CCNC
CDC6
DDI1
DDX58
DIABLO
DTX3
DTX3L
DZIP3
EXOSC7
FZR1
HTT
ITCH
ITSN1
KRIT1
LRSAM1
MAP3K1
MARCHF3
MARCHF7
MDM2
MEOX2
MID1
MID2
MIPOL1
MKRN2
MKRN3
NEDD4L
NEDD8
NFKB1
NUB1
PAX6
PIAS4
PICK1
PJA1
PRKN
PRPF40A
PRRG4
RBCK1
RC3H2
REL
RING1
RLIM
RNF111
RNF114
RNF125
RNF138
RNF144A
RNF166
RNF167
RNF182
RNF183
RNF185
RNF2
RNF31
RNF32
RNF4
RNF41
RNF5
SDCBP
SENP1
SH3RF1
SIAH1
SMURF1
TP53
TRAF7
TRAIP
TRIM2
TRIM27
TRIM3
TRIM31
TRIM34
TRIM35
TRIM39
TRIM43
TRIM5
TRIM50
TRIM63
TSN
UBA1
UBB
UBE2I
UBOX5
UHRF2
USP1
WWP2
ZDHHC17
ZNF384
Entrez ID
53840
3093
HPRD ID
16141
04165
Ensembl ID
ENSG00000258659
ENSG00000078140
Uniprot IDs
Q9BYJ4
B3KSH4
B4DIZ2
P61086
PDB IDs
2EGP
1YLA
2O25
3E46
3F92
3K9O
3K9P
5DFL
6IF1
6JB6
6JB7
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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