PLSCR1 and KIF1A

Data Source:
BioGRID (two hybrid)

		PLSCR1	KIF1A
Description		phospholipid scramblase 1	kinesin family member 1A
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Integral Component Of Plasma Membrane Membrane Membrane Raft Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix Extracellular Exosome	Cytosol Kinesin Complex Microtubule Synaptic Vesicle Axon Dendrite Neuronal Cell Body Extrinsic Component Of Neuronal Dense Core Vesicle Membrane Postsynapse Neuronal Dense Core Vesicle Axon Cytoplasm
	Molecular Function	Magnesium Ion Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Virus Receptor Activity DNA Binding Nuclease Activity Epidermal Growth Factor Receptor Binding Calcium Ion Binding Protein Binding Zinc Ion Binding SH3 Domain Binding Phospholipid Scramblase Activity Enzyme Binding Lead Ion Binding CD4 Receptor Binding Mercury Ion Binding	Motor Activity Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Identical Protein Binding
	Biological Process	Phosphatidylserine Biosynthetic Process Apoptotic Process Acute-phase Response Response To Lead Ion Positive Regulation Of Gene Expression Plasma Membrane Phospholipid Scrambling Platelet Activation Regulation Of Mast Cell Activation Response To Interferon-beta Negative Regulation Of Viral Genome Replication Positive Regulation Of Innate Immune Response Positive Regulation Of Transcription By RNA Polymerase II Viral Entry Into Host Cell Negative Regulation Of Phagocytosis Defense Response To Virus Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Phosphatidylserine Exposure On Apoptotic Cell Surface Nucleic Acid Phosphodiester Bond Hydrolysis Positive Regulation Of Chromosome Separation Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity	Microtubule-based Movement Anterograde Axonal Transport Vesicle-mediated Transport Interkinetic Nuclear Migration Cytoskeleton-dependent Intracellular Transport Regulation Of Dendritic Spine Development Regulation Of Dendritic Spine Morphogenesis Protein Transport Along Microtubule Dense Core Granule Cytoskeletal Transport Anterograde Neuronal Dense Core Vesicle Transport Retrograde Neuronal Dense Core Vesicle Transport
Pathways			COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs			Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate Phosphoaminophosphonic Acid-Adenylate Ester
Diseases
GWAS		Gut microbiota (beta diversity) ( 27723756)	Height ( 31562340) Response to placebo treatment in childhood asthma (FVC change) ( 31557306)
Interacting Genes		129 interacting genes: ABL1 ADAMTSL4 ADCY7 ANXA11 APP ARNT2 ATG12 ATN1 BACE1 BCL6B C10orf62 CATSPER1 CCDC33 CCER1 CDC42EP1 CHRD CNTFR CPSF6 CRK CRKL CRY1 CTBP1-DT CTSZ DAZAP2 DDIAS DEF6 DEPP1 DHRS1 DLK2 DMRT3 DOCK2 DTX2 EFEMP2 EGFR ENKD1 EP300 ESR2 EWSR1 EXD3 FAM107A FBLN1 FBXL18 FRAT1 FRS3 GDPD5 GLRX3 GNAI2 GPRIN2 HEY2 HOXA1 HOXA9 HOXB6 HRG ILF3 INTS11 IP6K2 IQCN KIF1A KRTAP10-11 KRTAP10-3 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP9-2 LASP1 LCE2D LCE3C LCE4A LGALS9C LINC00663 LINC01547 LONRF1 MAPK6 MED15 MGAT5B MVP NECAP2 NEU4 NOC4L NPDC1 NR0B2 NTN4 OGDH P2RY6 PCED1A PGLS PHLDA1 PITX1 PKD2 PLSCR3 PLSCR4 PML PRKCD PRR13 RAMAC RASD1 RBL1 RERE RGS3 RXRB SCNM1 SF1 SHC1 SLC25A6 SLC35A2 SLPI SMARCC1 SMCP SPATA8 SPG7 SPRY2 SRC STK16 TFG TRAF4 TRIM42 VASP VPS37C VSIR YIPF3 ZBTB16 ZNF417 ZNF581 ZNF587 ZNF638 ZNF688 ZNF764	26 interacting genes: ADAMTSL4 AR ESR1 FXR2 GIT1 MDFI MED1 MID2 MKRN3 MTUS2 NOTCH2NLA PLSCR1 PPARG PSMA3 RBPMS RFX6 RGS20 RNF31 RXRA SP1 SPRY2 TNS2 TRAF1 TRIM27 TRIP6 TSPOAP1
Entrez ID		5359	547
HPRD ID		08855	03156
Ensembl ID		ENSG00000188313	ENSG00000130294
Uniprot IDs		O15162	A0A3B3IT28 A0A3B3ITE5 A0A3B3IU40 Q12756
PDB IDs		1Y2A	4EGX 4EJQ 4UXO 4UXP 4UXR 4UXS
Enriched GO Terms of Interacting Partners?
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