KIF1A and RGS20

Data Source:
BioGRID (two hybrid)

		KIF1A	RGS20
Description		kinesin family member 1A	regulator of G protein signaling 20
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Kinesin Complex Microtubule Synaptic Vesicle Axon Dendrite Neuronal Cell Body Extrinsic Component Of Neuronal Dense Core Vesicle Membrane Postsynapse Neuronal Dense Core Vesicle Axon Cytoplasm	Nucleus Cytoplasm Trans-Golgi Network Plasma Membrane
	Molecular Function	Motor Activity Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Identical Protein Binding	GTPase Activity GTPase Activator Activity Protein Binding
	Biological Process	Microtubule-based Movement Anterograde Axonal Transport Vesicle-mediated Transport Interkinetic Nuclear Migration Cytoskeleton-dependent Intracellular Transport Regulation Of Dendritic Spine Development Regulation Of Dendritic Spine Morphogenesis Protein Transport Along Microtubule Dense Core Granule Cytoskeletal Transport Anterograde Neuronal Dense Core Vesicle Transport Retrograde Neuronal Dense Core Vesicle Transport	G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity
Pathways		COPI-dependent Golgi-to-ER retrograde traffic Kinesins	G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events
Drugs		Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate Phosphoaminophosphonic Acid-Adenylate Ester
Diseases
GWAS		Height ( 31562340) Response to placebo treatment in childhood asthma (FVC change) ( 31557306)	Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) Chronic obstructive pulmonary disease ( 32222710) Serum uric acid levels ( 29559957) Urinary albumin-to-creatinine ratio ( 26631737)
Interacting Genes		26 interacting genes: ADAMTSL4 AR ESR1 FXR2 GIT1 MDFI MED1 MID2 MKRN3 MTUS2 NOTCH2NLA PLSCR1 PPARG PSMA3 RBPMS RFX6 RGS20 RNF31 RXRA SP1 SPRY2 TNS2 TRAF1 TRIM27 TRIP6 TSPOAP1	54 interacting genes: ABHD17A ADRB2 ALPP AQP1 CATSPER1 COL8A1 CRCT1 CREB5 FASLG GLRX3 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ HOXA1 HRG HSPD1 INS KIF1A KLHL38 KRTAP4-2 KRTAP5-11 KRTAP5-6 KRTAP5-9 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3C LCE3D LCE3E LCE4A LCE5A LNX1 MAPKBP1 NECTIN2 NECTIN3 NEK8 NUFIP2 OSTM1 OTX1 PTGER3 PTPMT1 RANBP3 STMN2 TBC1D16 VASN
Entrez ID		547	8601
HPRD ID		03156	06225
Ensembl ID		ENSG00000130294	ENSG00000147509
Uniprot IDs		A0A3B3IT28 A0A3B3ITE5 A0A3B3IU40 Q12756	B3KSW4 H9NIM5 O76081
PDB IDs		4EGX 4EJQ 4UXO 4UXP 4UXR 4UXS
Enriched GO Terms of Interacting Partners?
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