ATP6V0B and BPI

Data Source:
BioGRID (affinity chromatography technology)

		ATP6V0B	BPI
Description		ATPase H+ transporting V0 subunit b	bactericidal permeability increasing protein
Image		No pdb structure
GO Annotations	Cellular Component	Vacuolar Membrane Endosome Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain	Extracellular Region Extracellular Space Membrane Azurophil Granule Lumen Specific Granule Lumen Extracellular Exosome
	Molecular Function	Transporter Activity Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism	Lipopolysaccharide Binding
	Biological Process	Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport	Antimicrobial Humoral Response Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of Interleukin-6 Production Negative Regulation Of Interleukin-8 Production Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Macrophage Activation Neutrophil Degranulation Innate Immune Response Defense Response To Gram-negative Bacterium
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport	Toll Like Receptor 4 (TLR4) Cascade Neutrophil degranulation Antimicrobial peptides
Drugs		Tiludronic acid	Di-Stearoyl-3-Sn-Phosphatidylcholine
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026)	Basophil count ( 32888494) Blood protein levels ( 29875488) Carboplatin disposition in epthelial ovarian cancer ( 29367611) Monocyte percentage of white cells ( 32888494) White blood cell count ( 32888494)
Interacting Genes		28 interacting genes: ADGRG3 ADRB2 APOD COL4A5 EMP1 FAM210B FAS GJA8 GPR42 GPR61 INSIG2 IRAK3 KLRC1 MFF MIP MS4A3 MTNR1B NRM SLC10A1 SLC2A5 SNTA1 SPACA1 STOM TM4SF19 TMEM242 VMA21 YWHAE YWHAG	1 interacting genes: PRSS2
Entrez ID		533	671
HPRD ID		04759	00174
Ensembl ID		ENSG00000117410	ENSG00000101425
Uniprot IDs		E9PNL3 Q99437	P17213
PDB IDs			1BP1 1EWF
Enriched GO Terms of Interacting Partners?
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