ADGRG3 and ATP6V0B

Data Source:
BioGRID (two hybrid)

		ADGRG3	ATP6V0B
Description		adhesion G protein-coupled receptor G3	ATPase H+ transporting V0 subunit b
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Specific Granule Membrane	Vacuolar Membrane Endosome Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding	Transporter Activity Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway B Cell Differentiation Regulation Of Cell Migration Negative Regulation Of CREB Transcription Factor Activity Neutrophil Degranulation Negative Regulation Of NIK/NF-kappaB Signaling	Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport
Pathways		Neutrophil degranulation	ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		12 interacting genes: ATP6V0B C3orf52 C4orf3 CTXN3 GIMAP5 LHFPL5 PLP1 RPRM SEC22A TEX264 UPK2 VSTM1	28 interacting genes: ADGRG3 ADRB2 APOD COL4A5 EMP1 FAM210B FAS GJA8 GPR42 GPR61 INSIG2 IRAK3 KLRC1 MFF MIP MS4A3 MTNR1B NRM SLC10A1 SLC2A5 SNTA1 SPACA1 STOM TM4SF19 TMEM242 VMA21 YWHAE YWHAG
Entrez ID		222487	533
HPRD ID		17073	04759
Ensembl ID		ENSG00000182885	ENSG00000117410
Uniprot IDs		B4DVW2 F8W8F7 Q86Y34	E9PNL3 Q99437
PDB IDs
Enriched GO Terms of Interacting Partners?
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