PFDN4 and VBP1

Data Source:
BioGRID (biochemical, two hybrid)

		PFDN4	VBP1
Description		prefoldin subunit 4	VHL binding protein 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Cytosol Prefoldin Complex	Nucleus Cytoplasm Cytosol Polysome Prefoldin Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Amyloid-beta Binding Protein Binding Unfolded Protein Binding Chaperone Binding	Amyloid-beta Binding Protein Binding Tubulin Binding Unfolded Protein Binding
	Biological Process	Protein Folding Negative Regulation Of Amyloid Fibril Formation	Protein Folding Microtubule-based Process Tubulin Complex Assembly Negative Regulation Of Amyloid Fibril Formation
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC	Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS		Atopic dermatitis ( 23042114) Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Creatinine levels ( 31015462) Modified Stumvoll Insulin Sensitivity Index (BMI interaction) ( 27416945) Obesity-related traits ( 23251661)
Interacting Genes		7 interacting genes: ACTB ERBB3 PFDN2 RFPL3 TUBA4A TUBB VBP1	31 interacting genes: C1orf109 DDIT4L EFHC1 ENKD1 FGF1 GLIS2 GPANK1 IKZF3 LMO1 LMO2 LMO3 MEOX2 MISP MKNK2 MSH4 MYOZ1 PFDN2 PFDN4 PFDN5 PIK3R3 PNMA1 PRKAB2 SUOX TCEANC TSC22D4 UBL7 VEZF1 VHL XRCC6 ZNF410 ZNF576
Entrez ID		5203	7411
HPRD ID		05358	02135
Ensembl ID		ENSG00000101132	ENSG00000155959
Uniprot IDs		Q9NQP4	D3DWY7 P61758 Q6FH24
PDB IDs		6NR8 6NR9 6NRB 6NRC 6NRD	6NR8 6NR9 6NRB 6NRC 6NRD
Enriched GO Terms of Interacting Partners?
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