VBP1 and PFDN2

Data Source:
BioGRID (biochemical, affinity chromatography technology, two hybrid, biochemical)
HPRD (in vitro)

		VBP1	PFDN2
Description		VHL binding protein 1	prefoldin subunit 2
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Polysome Prefoldin Complex Intracellular Membrane-bounded Organelle	Nucleus Cytoplasm Mitochondrion Cytosol Prefoldin Complex
	Molecular Function	Amyloid-beta Binding Protein Binding Tubulin Binding Unfolded Protein Binding	Amyloid-beta Binding Protein Binding Protein Folding Chaperone Unfolded Protein Binding
	Biological Process	Protein Folding Microtubule-based Process Tubulin Complex Assembly Negative Regulation Of Amyloid Fibril Formation	Protein Folding Positive Regulation Of Cytoskeleton Organization Negative Regulation Of Amyloid Fibril Formation
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC	Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS
Interacting Genes		31 interacting genes: C1orf109 DDIT4L EFHC1 ENKD1 FGF1 GLIS2 GPANK1 IKZF3 LMO1 LMO2 LMO3 MEOX2 MISP MKNK2 MSH4 MYOZ1 PFDN2 PFDN4 PFDN5 PIK3R3 PNMA1 PRKAB2 SUOX TCEANC TSC22D4 UBL7 VEZF1 VHL XRCC6 ZNF410 ZNF576	9 interacting genes: DBI ERBB3 MAP3K3 PFDN1 PFDN4 PFDN5 SNCA VBP1 ZNF726
Entrez ID		7411	5202
HPRD ID		02135	09658
Ensembl ID		ENSG00000155959	ENSG00000143256
Uniprot IDs		D3DWY7 P61758 Q6FH24	B1AQP2 Q9UHV9
PDB IDs		6NR8 6NR9 6NRB 6NRC 6NRD	6NR8 6NR9 6NRB 6NRC 6NRD
Enriched GO Terms of Interacting Partners?
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