VBP1 and MKNK2

Data Source:
BioGRID (two hybrid)

		VBP1	MKNK2
Description		VHL binding protein 1	MAPK interacting serine/threonine kinase 2
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Polysome Prefoldin Complex Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Cytoplasm Nuclear Body PML Body
	Molecular Function	Amyloid-beta Binding Protein Binding Tubulin Binding Unfolded Protein Binding	Protein Serine/threonine Kinase Activity Calmodulin-dependent Protein Kinase Activity Protein Binding Calmodulin Binding ATP Binding Calcium-dependent Protein Serine/threonine Kinase Activity Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Protein Folding Microtubule-based Process Tubulin Complex Assembly Negative Regulation Of Amyloid Fibril Formation	Regulation Of Translation Protein Phosphorylation Cell Surface Receptor Signaling Pathway Peptidyl-serine Phosphorylation Hemopoiesis Intracellular Signal Transduction Protein Autophosphorylation Cellular Response To Arsenic-containing Substance Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC
Drugs			Fostamatinib
Diseases
GWAS			Nonsyndromic cleft lip with or without cleft palate ( 28087736)
Interacting Genes		31 interacting genes: C1orf109 DDIT4L EFHC1 ENKD1 FGF1 GLIS2 GPANK1 IKZF3 LMO1 LMO2 LMO3 MEOX2 MISP MKNK2 MSH4 MYOZ1 PFDN2 PFDN4 PFDN5 PIK3R3 PNMA1 PRKAB2 SUOX TCEANC TSC22D4 UBL7 VEZF1 VHL XRCC6 ZNF410 ZNF576	13 interacting genes: CUL2 EIF4E EIF4G1 ESR1 ESR2 MAPK1 MAPK14 MAPK8 MESD PSMA1 RBX1 RPL7A VBP1
Entrez ID		7411	2872
HPRD ID		02135	05459
Ensembl ID		ENSG00000155959	ENSG00000099875
Uniprot IDs		D3DWY7 P61758 Q6FH24	B3KS07 Q9HBH9
PDB IDs		6NR8 6NR9 6NRB 6NRC 6NRD	2AC3 2AC5 2HW7 6CJ5 6CJE 6CJH 6CJW 6CJY 6CK3 6CK6 6CKI 6JLR
Enriched GO Terms of Interacting Partners?
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