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CFP and KRTAP11-1
Data Source:
BioGRID
(two hybrid)
CFP
KRTAP11-1
Description
complement factor properdin
keratin associated protein 11-1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Endoplasmic Reticulum Lumen
Specific Granule Lumen
Collagen-containing Extracellular Matrix
Tertiary Granule Lumen
Cytosol
Intermediate Filament
Molecular Function
Protein Binding
Protein Binding
Biological Process
Immune Response
Complement Activation
Complement Activation, Alternative Pathway
Regulation Of Complement Activation
Defense Response To Bacterium
Neutrophil Degranulation
Keratinization
Pathways
Alternative complement activation
Activation of C3 and C5
Defective B3GALTL causes Peters-plus syndrome (PpS)
O-glycosylation of TSR domain-containing proteins
Neutrophil degranulation
Regulation of Complement cascade
Keratinization
Drugs
Diseases
Alternative complement pathway component defects, including the following four diseases: Factor B deficiency; Factor D deficiency; Factor H deficiency; Properdin deficiency
GWAS
Height (
28552196
)
Interacting Genes
32 interacting genes:
BANF2
C3
CFAP206
CFB
CYSRT1
FHL5
FKBP6
GEMIN4
GNE
HEXIM2
HOXA1
KCTD9
KLHL38
KRTAP11-1
KRTAP12-2
KRTAP3-1
KRTAP6-2
LCE1A
LONRF1
MID2
MTOR
NEK6
NOXA1
PRKAB2
RECK
SMARCC1
SPAG8
STK16
TRIP13
VENTX
ZNF330
ZNF414
104 interacting genes:
AGR3
ANAPC11
ANKS1A
ASB13
ATG9A
ATXN1L
BEX2
CERK
CFP
CHERP
CRYBA1
CRYBA2
CSKMT
CYSRT1
DHRS1
DTX2
DUSP21
EFEMP2
ENKD1
ETFDH
FAM222B
FANCL
FASLG
FBLN1
FNDC3B
FOXH1
FRS3
GATA2
GNE
GPS2
GPSM3
GRN
HEY2
HOXA1
HOXC8
HR
KLHL38
KRT83
KRTAP10-5
KRTAP10-8
KRTAP12-1
KRTAP12-3
KRTAP12-4
KRTAP13-2
KRTAP15-1
KRTAP26-1
KRTAP4-11
KRTAP4-2
KRTAP5-11
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-9
KRTAP6-1
KRTAP6-2
KRTAP6-3
KRTAP9-2
KRTAP9-3
KRTAP9-8
LCE1A
LCE1B
LCE1F
LCE2A
LCE3A
LCE3C
LGALS4
LIMS3
LIMS4
LMO4
MEIS2
MICOS10-NBL1
NBL1
NUFIP2
OIT3
OLIG3
OR7A17
OTX1
PCSK5
PLA2G10
PLSCR3
RBPMS
RBPMS2
RNF38
SLC13A5
SNRPC
SPAG8
SPRY1
STK16
TBX6
TEKT4
TENT5D
TFAP2D
TLE5
TLX3
TNS2
TRIM54
VASN
VENTX
VGLL3
VWC2L
WWOX
YIPF3
ZDHHC17
ZIC1
Entrez ID
5199
337880
HPRD ID
02308
11196
Ensembl ID
ENSG00000126759
ENSG00000182591
Uniprot IDs
A0A0S2Z4I5
P27918
Q8IUC1
PDB IDs
1W0R
1W0S
6RUR
6RUS
6RUV
6RV6
6S08
6S0A
6S0B
6SEJ
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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