CFP and BANF2

Data Source:
BioGRID (two hybrid)

		CFP	BANF2
Description		complement factor properdin	BANF family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Specific Granule Lumen Collagen-containing Extracellular Matrix Tertiary Granule Lumen	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding	DNA Binding
	Biological Process	Immune Response Complement Activation Complement Activation, Alternative Pathway Regulation Of Complement Activation Defense Response To Bacterium Neutrophil Degranulation	Chromosome Segregation Chromosome Condensation
Pathways		Alternative complement activation Activation of C3 and C5 Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins Neutrophil degranulation Regulation of Complement cascade
Drugs
Diseases		Alternative complement pathway component defects, including the following four diseases: Factor B deficiency; Factor D deficiency; Factor H deficiency; Properdin deficiency
GWAS			Apolipoprotein B levels ( 32203549) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Heel bone mineral density ( 30598549) LDL cholesterol levels ( 32203549 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
Interacting Genes		32 interacting genes: BANF2 C3 CFAP206 CFB CYSRT1 FHL5 FKBP6 GEMIN4 GNE HEXIM2 HOXA1 KCTD9 KLHL38 KRTAP11-1 KRTAP12-2 KRTAP3-1 KRTAP6-2 LCE1A LONRF1 MID2 MTOR NEK6 NOXA1 PRKAB2 RECK SMARCC1 SPAG8 STK16 TRIP13 VENTX ZNF330 ZNF414	17 interacting genes: ADAMTSL4 BANF1 BEND7 CFP CRX CRYBA1 DDIT4L DNAAF4 DUSP23 INCA1 KRTAP13-1 MTUS2 NTAQ1 PRDM6 PSMA1 SERTAD1 TCF4
Entrez ID		5199	140836
HPRD ID		02308	12759
Ensembl ID		ENSG00000126759	ENSG00000125888
Uniprot IDs		A0A0S2Z4I5 P27918	A0A140VK85 Q9H503
PDB IDs		1W0R 1W0S 6RUR 6RUS 6RUV 6RV6 6S08 6S0A 6S0B 6SEJ
Enriched GO Terms of Interacting Partners?
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