PHAX and ZWINT

Data Source:
BioGRID (two hybrid)

		PHAX	ZWINT
Description		phosphorylated adaptor for RNA export	ZW10 interacting kinetochore protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Centrosome Cytosol Cajal Body Neuronal Cell Body	Kinetochore Condensed Chromosome Kinetochore Nucleoplasm Cytoplasm Cytosol Nuclear Body Dendrite
	Molecular Function	RNA Binding Protein Binding Toxic Substance Binding	Protein Binding Protein N-terminus Binding
	Biological Process	SnRNA Export From Nucleus Protein Transport SnRNA Transcription By RNA Polymerase II Nuclear Export	Mitotic Sister Chromatid Segregation Mitotic Cell Cycle Checkpoint Mitotic Spindle Assembly Checkpoint Cell Division Establishment Of Localization In Cell
Pathways		snRNP Assembly RNA polymerase II transcribes snRNA genes	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Colorectal cancer ( 30529582)	Cardiac hypertrophy ( 21348951) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Liver fibrosis (total hepatic collagen content) ( 32953199)
Interacting Genes		16 interacting genes: ASPSCR1 CDC42 GADD45G GRB7 MKNK1 NSFL1C PDPK1 RAD23A RPS6KA1 STK3 TNFSF11 TULP3 UBXN2A VAV1 XPO1 ZWINT	17 interacting genes: APP BCAS2 BFSP1 CCHCR1 CLU DSN1 FAM90A1 KRT75 LIG4 MAFB MIS12 MSGN1 NDC80 NUP54 PHAX TSG101 ZW10
Entrez ID		51808	11130
HPRD ID		15122	18366
Ensembl ID		ENSG00000164902	ENSG00000122952
Uniprot IDs		Q9H814	O95229
PDB IDs		2XC7
Enriched GO Terms of Interacting Partners?
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