LUC7L3 and SRSF1

Data Source:
HPRD (two hybrid, in vitro)

		LUC7L3	SRSF1
Description		LUC7 like 3 pre-mRNA splicing factor	serine and arginine rich splicing factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm U1 SnRNP Nuclear Speck U2-type Prespliceosome	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Exon-exon Junction Complex Catalytic Step 2 Spliceosome
	Molecular Function	DNA Binding RNA Binding MRNA Binding Protein Binding	RNA Binding MRNA Binding Protein Binding DNA Topoisomerase Binding
	Biological Process	MRNA Splice Site Selection RNA Splicing	Alternative MRNA Splicing, Via Spliceosome MRNA 5'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Splice Site Selection MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs			Copper
Diseases
GWAS		Mild to moderate chronic kidney disease ( 31178898)	Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		9 interacting genes: CLK1 ITSN2 MLH1 RNPS1 SRPK1 SRPK2 SRSF1 TLR10 YWHAG	43 interacting genes: AKAP17A APP BCL10 C1QBP CACNA1A CD8A CDC42 CDK12 CDK6 CLK1 DIDO1 DYRK1A GEMIN2 HIPK3 HNRNPA0 LNX1 LUC7L3 NFYA NXF1 PPARG PRPF4 PRPF4B PSIP1 RNPS1 SCAF11 SNRNP70 SREK1 SRPK1 SRPK2 SRSF10 SRSF11 SRSF4 SRSF5 TCERG1 TNPO3 TOP1 TP53 TRA2B U2AF1 U2AF2 XBP1 YTHDC1 ZRSR2
Entrez ID		51747	6426
HPRD ID		16759	02887
Ensembl ID		ENSG00000108848	ENSG00000136450
Uniprot IDs		A8K3C5 J3KPP4 O95232 Q86Y74	Q07955 Q59FA2
PDB IDs			1X4A 2M7S 2M8D 2O3D 3BEG 4C0O
Enriched GO Terms of Interacting Partners?
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