DNAJB11 and DDAH2

Data Source:
BioGRID (two hybrid)

		DNAJB11	DDAH2
Description		DnaJ heat shock protein family (Hsp40) member B11	dimethylarginine dimethylaminohydrolase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Membrane Chaperone Complex	Mitochondrion Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Unfolded Protein Binding Misfolded Protein Binding	Catalytic Activity Protein Binding Dimethylargininase Activity Amino Acid Binding
	Biological Process	Protein Folding Positive Regulation Of ATPase Activity IRE1-mediated Unfolded Protein Response Protein Maturation	Citrulline Metabolic Process Arginine Metabolic Process Arginine Catabolic Process Nitric Oxide Biosynthetic Process Nitric Oxide Mediated Signal Transduction Negative Regulation Of Apoptotic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric-oxide Synthase Activity
Pathways		XBP1(S) activates chaperone genes	eNOS activation
Drugs			Citrulline
Diseases
GWAS			Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Ulcerative colitis ( 28067908)
Interacting Genes		24 interacting genes: ANKZF1 APOBEC1 BAG6 CEP70 COL6A1 CRMP1 DDAH2 DNAJC13 DRAP1 EIF3D EZH2 FAF1 GRB2 HSPA1A HTN3 PAXIP1 PTN SIMC1 SNX5 SPRED1 SUMO4 UBQLN4 UBR1 ZZZ3	27 interacting genes: ACTN3 ANXA7 ATP1B1 CDC73 CDK4 CDKN1A DNAJB11 FANCL GADD45G IGFN1 MAP3K20 MKNK1 NOXA1 PIN1 PRKAB2 RAP1B RCC1 RPS6KA1 RPS6KA5 SMN1 STK3 TAF1D TK1 TNFSF11 TRIP13 TSC22D1 VAC14
Entrez ID		51726	23564
HPRD ID		07485	09204
Ensembl ID		ENSG00000090520	ENSG00000213722
Uniprot IDs		Q9UBS4	O95865 V9HW53
PDB IDs
Enriched GO Terms of Interacting Partners?
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