DNAJB11 and DRAP1

Data Source:
BioGRID (two hybrid)

		DNAJB11	DRAP1
Description		DnaJ heat shock protein family (Hsp40) member B11	DR1 associated protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Membrane Chaperone Complex	Nucleus Negative Cofactor 2 Complex RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Protein Binding Unfolded Protein Binding Misfolded Protein Binding	Core Promoter Sequence-specific DNA Binding RNA Polymerase II General Transcription Initiation Factor Binding DNA Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Identical Protein Binding Protein Heterodimerization Activity
	Biological Process	Protein Folding Positive Regulation Of ATPase Activity IRE1-mediated Unfolded Protein Response Protein Maturation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		XBP1(S) activates chaperone genes	Signaling by NODAL Signaling by Activin
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) Asthma ( 31959851) Eosinophil percentage of granulocytes ( 27863252) Multiple sclerosis ( 31604244) Neutrophil percentage of granulocytes ( 27863252) Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		24 interacting genes: ANKZF1 APOBEC1 BAG6 CEP70 COL6A1 CRMP1 DDAH2 DNAJC13 DRAP1 EIF3D EZH2 FAF1 GRB2 HSPA1A HTN3 PAXIP1 PTN SIMC1 SNX5 SPRED1 SUMO4 UBQLN4 UBR1 ZZZ3	31 interacting genes: APP ARHGEF10L CDKN2C DNAJB11 DR1 FBXO7 FEZ1 FEZ2 FOXH1 GTF2B LMO2 LNX1 LNX2 MCRS1 MORF4L1 NCK2 NFYB PICK1 PIK3R3 PLEKHF2 POLE3 RPL9 SDCBP SRPK2 TAF9 TAF9B TBP TK1 TNFRSF14 TTF2 ZEB1
Entrez ID		51726	10589
HPRD ID		07485	03796
Ensembl ID		ENSG00000090520	ENSG00000175550
Uniprot IDs		Q9UBS4	Q14919
PDB IDs			1JFI
Enriched GO Terms of Interacting Partners?
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