NSG2 and UCHL3

Data Source:
BioGRID (two hybrid)

		NSG2	UCHL3
Description		neuronal vesicle trafficking associated 2	ubiquitin C-terminal hydrolase L3
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Early Endosome Late Endosome Golgi Apparatus Integral Component Of Membrane Dendrite Cytoplasmic Vesicle Membrane Early Endosome Membrane Multivesicular Body Membrane Trans-Golgi Network Membrane Lysosomal Lumen Golgi Cis Cisterna Membrane	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding Clathrin Light Chain Binding	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Peptidase Activity NEDD8-specific Protease Activity Ubiquitin Binding
	Biological Process	Dopamine Receptor Signaling Pathway Endosomal Transport Clathrin Coat Assembly	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Deubiquitination Protein Phosphopantetheinylation Protein Catabolic Process Post-translational Protein Modification
Pathways			UCH proteinases Synthesis of active ubiquitin: roles of E1 and E2 enzymes Neddylation
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Diffusing capacity of carbon monoxide ( 30694715)	Diabetic retinopathy ( 23562823) Metabolite levels ( 23823483)
Interacting Genes		17 interacting genes: ANKRD46 APOC1 C3orf52 CLEC7A HCFC1R1 NDUFA2 RIF1 RPS27 RRH SERPINH1 SLC35F6 STX18 SUPT4H1 TNNT1 TSPAN6 UCHL3 ZNF768	20 interacting genes: ATM ATXN7L3 CDH1 FOXM1 LONRF1 NEDD8 NSG2 PJA1 PLA2G2A POGK RAD51 TRIM27 TRIM54 TRIM55 TRIM63 UBE2S USP15 USP21 USP28 XRCC5
Entrez ID		51617	7347
HPRD ID		13664	04367
Ensembl ID		ENSG00000170091	ENSG00000118939
Uniprot IDs		Q9Y328	A0A087WTB8 A0A140VJZ4 P15374
PDB IDs			1UCH 1XD3 6ISU 6QML
Enriched GO Terms of Interacting Partners?
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