TRMT6 and FOXJ1

Data Source:
BioGRID (two hybrid)

		TRMT6	FOXJ1
Description		tRNA methyltransferase 6	forkhead box J1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm TRNA (m1A) Methyltransferase Complex	Chromatin Nucleus
	Molecular Function	RNA Binding Protein Binding TRNA (adenine-N1-)-methyltransferase Activity	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	TRNA Modification TRNA Methylation MRNA Methylation	Negative Regulation Of Transcription By RNA Polymerase II Central Tolerance Induction Negative Regulation Of Germinal Center Formation Positive Regulation Of Central B Cell Tolerance Induction Negative Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of Transcription By RNA Polymerase II Humoral Immune Response Spermatogenesis Determination Of Left/right Symmetry Pattern Specification Process Brain Development Heart Development Actin Cytoskeleton Organization Ciliary Basal Body Organization Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interleukin-6 Production Negative Regulation Of T Cell Differentiation In Thymus Cellular Protein Localization Axoneme Assembly Establishment Of Apical/basal Cell Polarity Metanephric Part Of Ureteric Bud Development Negative Regulation Of T Cell Proliferation Motile Cilium Assembly Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of B Cell Activation Leukocyte Migration Cilium Assembly Lung Epithelium Development Epithelium Development Left/right Pattern Formation Glomerular Parietal Epithelial Cell Development Activation Of GTPase Activity Positive Regulation Of Lung Ciliated Cell Differentiation
Pathways		tRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS		Menarche and menopause (age at onset) ( 19448621) Uterine fibroids ( 31649266)
Interacting Genes		3 interacting genes: FOXJ1 HHEX TRMT61A	8 interacting genes: NMRAL1 OIP5 RFX2 RPUSD1 SLC37A3 THRA TRMT6 TWF2
Entrez ID		51605	2302
HPRD ID		13027	03798
Ensembl ID		ENSG00000089195	ENSG00000129654
Uniprot IDs		Q9UJA5	A0A024R8P1 Q92949
PDB IDs		5CCB 5CCX 5CD1
Enriched GO Terms of Interacting Partners?
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