FOXJ1 and TRMT6

Data Source:
BioGRID (two hybrid)

		FOXJ1	TRMT6
Description		forkhead box J1	tRNA methyltransferase 6
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Nucleoplasm TRNA (m1A) Methyltransferase Complex
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding	RNA Binding Protein Binding TRNA (adenine-N1-)-methyltransferase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Central Tolerance Induction Negative Regulation Of Germinal Center Formation Positive Regulation Of Central B Cell Tolerance Induction Negative Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of Transcription By RNA Polymerase II Humoral Immune Response Spermatogenesis Determination Of Left/right Symmetry Pattern Specification Process Brain Development Heart Development Actin Cytoskeleton Organization Ciliary Basal Body Organization Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interleukin-6 Production Negative Regulation Of T Cell Differentiation In Thymus Cellular Protein Localization Axoneme Assembly Establishment Of Apical/basal Cell Polarity Metanephric Part Of Ureteric Bud Development Negative Regulation Of T Cell Proliferation Motile Cilium Assembly Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of B Cell Activation Leukocyte Migration Cilium Assembly Lung Epithelium Development Epithelium Development Left/right Pattern Formation Glomerular Parietal Epithelial Cell Development Activation Of GTPase Activity Positive Regulation Of Lung Ciliated Cell Differentiation	TRNA Modification TRNA Methylation MRNA Methylation
Pathways			tRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS			Menarche and menopause (age at onset) ( 19448621) Uterine fibroids ( 31649266)
Interacting Genes		8 interacting genes: NMRAL1 OIP5 RFX2 RPUSD1 SLC37A3 THRA TRMT6 TWF2	3 interacting genes: FOXJ1 HHEX TRMT61A
Entrez ID		2302	51605
HPRD ID		03798	13027
Ensembl ID		ENSG00000129654	ENSG00000089195
Uniprot IDs		A0A024R8P1 Q92949	Q9UJA5
PDB IDs			5CCB 5CCX 5CD1
Enriched GO Terms of Interacting Partners?
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