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FOXJ1 and THRA
Data Source:
BioGRID
(two hybrid)
FOXJ1
THRA
Description
forkhead box J1
thyroid hormone receptor alpha
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Chromatin
Nucleus
Nucleoplasm
Cytosol
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Nuclear Receptor Activity
Protein Binding
Transcription Factor Binding
Zinc Ion Binding
TBP-class Protein Binding
Protein Domain Specific Binding
Chromatin DNA Binding
Protein-containing Complex Binding
Thyroid Hormone Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Central Tolerance Induction
Negative Regulation Of Germinal Center Formation
Positive Regulation Of Central B Cell Tolerance Induction
Negative Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin
Regulation Of Transcription By RNA Polymerase II
Humoral Immune Response
Spermatogenesis
Determination Of Left/right Symmetry
Pattern Specification Process
Brain Development
Heart Development
Actin Cytoskeleton Organization
Ciliary Basal Body Organization
Negative Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Interleukin-6 Production
Negative Regulation Of T Cell Differentiation In Thymus
Cellular Protein Localization
Axoneme Assembly
Establishment Of Apical/basal Cell Polarity
Metanephric Part Of Ureteric Bud Development
Negative Regulation Of T Cell Proliferation
Motile Cilium Assembly
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of B Cell Activation
Leukocyte Migration
Cilium Assembly
Lung Epithelium Development
Epithelium Development
Left/right Pattern Formation
Glomerular Parietal Epithelial Cell Development
Activation Of GTPase Activity
Positive Regulation Of Lung Ciliated Cell Differentiation
Negative Regulation Of Transcription By RNA Polymerase II
Cartilage Condensation
Ossification
Thyroid Hormone Mediated Signaling Pathway
Regulation Of Thyroid Hormone Mediated Signaling Pathway
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Learning Or Memory
Regulation Of Heart Contraction
Female Courtship Behavior
Response To Cold
Hormone-mediated Signaling Pathway
Negative Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly
Cell Differentiation
Erythrocyte Differentiation
Thyroid Gland Development
Regulation Of Myeloid Cell Apoptotic Process
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Female Receptivity
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Lipid Catabolic Process
Type I Pneumocyte Differentiation
Positive Regulation Of Cold-induced Thermogenesis
Negative Regulation Of DNA-templated Transcription, Initiation
Pathways
Nuclear Receptor transcription pathway
Drugs
Liothyronine
Levothyroxine
Dextrothyroxine
Amiodarone
Liotrix
KB-141
Dronedarone
Eprotirome
NRP409
Thyroid, porcine
Diseases
GWAS
Asthma (
31619474
)
Bipolar disorder (
31043756
)
Chronic obstructive pulmonary disease (
30804561
)
Pancreatic ductal adenocarcinoma (
30541042
)
White blood cell count (
21738480
)
Interacting Genes
8 interacting genes:
NMRAL1
OIP5
RFX2
RPUSD1
SLC37A3
THRA
TRMT6
TWF2
69 interacting genes:
-
AKAP13
AMOT
AMOTL2
ARID5A
BTG1
BUB3
C1D
CCND1
CD160
CDK7
CEP76
CLIC1
COPS2
CREB1
CREBBP
CUL1
DAP3
ESR1
FOXJ1
FUS
GRIP1
GTF2B
HDAC2
HDAC3
ITGB3BP
L3MBTL3
MED1
MED21
MED25
MEF2A
MEOX2
MTNR1B
NCOA1
NCOA2
NCOA6
NCOR1
NCOR2
NR0B2
NR2F1
NRIP1
NSD1
OASL
PML
POU2F1
PRKAR1B
PRKDC
PTGES3
RANBP9
RGN
RXRA
RXRB
RXRG
SELENOP
SLC16A2
SRC
SUV39H1
SYAP1
TACC1
TBL1X
TDG
TRIM24
TRIM63
TRIP11
TXNRD1
UBE2I
YWHAH
YWHAQ
ZBTB3
Entrez ID
2302
7067
HPRD ID
03798
07185
Ensembl ID
ENSG00000129654
ENSG00000126351
Uniprot IDs
A0A024R8P1
Q92949
P10827
Q6FH41
PDB IDs
1NAV
2H77
2H79
3HZF
3ILZ
3JZB
4LNW
4LNX
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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