RIF1 and NSG2

Data Source:
HPRD (two hybrid)

		RIF1	NSG2
Description		replication timing regulatory factor 1	neuronal vesicle trafficking associated 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Chromatin Condensed Chromosome Female Pronucleus Male Pronucleus Nucleus Nucleoplasm Cytoplasm Plasma Membrane Nuclear Body Nuclear Membrane Site Of Double-strand Break Spindle Midzone	Endosome Early Endosome Late Endosome Golgi Apparatus Integral Component Of Membrane Dendrite Cytoplasmic Vesicle Membrane Early Endosome Membrane Multivesicular Body Membrane Trans-Golgi Network Membrane Lysosomal Lumen Golgi Cis Cisterna Membrane
	Molecular Function	Protein Binding	Protein Binding Clathrin Light Chain Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Telomere Maintenance Double-strand Break Repair Via Nonhomologous End Joining Chromatin Silencing At Telomere Cellular Response To DNA Damage Stimulus Cell Cycle Stem Cell Population Maintenance Telomere Maintenance In Response To DNA Damage Positive Regulation Of Isotype Switching Positive Regulation Of Histone H3-K9 Methylation Cellular Response To Leukemia Inhibitory Factor Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining	Dopamine Receptor Signaling Pathway Endosomal Transport Clathrin Coat Assembly
Pathways		Nonhomologous End-Joining (NHEJ)
Drugs
Diseases
GWAS		Lung cancer ( 23143601) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483)	Blond vs. brown/black hair color ( 30531825) Diffusing capacity of carbon monoxide ( 30694715)
Interacting Genes		20 interacting genes: BRD7 CEP126 CHD3 DEFB1 FEZ1 GIT1 GNE GRB2 HAP1 LINC00839 NSG2 PABPC4 PIAS4 POT1 PPP1CA PPP1CC SETDB1 SMARCD1 SUMO2 TERF2IP	17 interacting genes: ANKRD46 APOC1 C3orf52 CLEC7A HCFC1R1 NDUFA2 RIF1 RPS27 RRH SERPINH1 SLC35F6 STX18 SUPT4H1 TNNT1 TSPAN6 UCHL3 ZNF768
Entrez ID		55183	51617
HPRD ID		10603	13664
Ensembl ID		ENSG00000080345	ENSG00000170091
Uniprot IDs		Q5UIP0	Q9Y328
PDB IDs
Enriched GO Terms of Interacting Partners?
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