AZIN1 and FANCC

Data Source:
BioGRID (two hybrid)

		AZIN1	FANCC
Description		antizyme inhibitor 1	FA complementation group C
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus Nucleoplasm Cytoplasm Cytosol Fanconi Anaemia Nuclear Complex
	Molecular Function	Ornithine Decarboxylase Activity Protein Binding Ornithine Decarboxylase Activator Activity	Protein Binding
	Biological Process	Regulation Of Cellular Amino Acid Metabolic Process Putrescine Biosynthetic Process From Ornithine Negative Regulation Of Protein Catabolic Process Regulation Of Catalytic Activity Positive Regulation Of Polyamine Transmembrane Transport	Myeloid Cell Homeostasis DNA Repair Nucleotide-excision Repair Germ Cell Development Removal Of Superoxide Radicals Cellular Response To Oxidative Stress Interstrand Cross-link Repair Brain Morphogenesis Protein-containing Complex Assembly Neuronal Stem Cell Population Maintenance
Pathways		Regulation of ornithine decarboxylase (ODC)	Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes
Drugs
Diseases			Fanconi anemia
GWAS		Airway imaging phenotypes ( 26030696) Apolipoprotein A1 levels ( 32203549) Granulocyte count ( 27863252) HDL cholesterol levels ( 32203549) Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Neutrophil count ( 27863252) PR interval ( 32439900) QT interval ( 24952745) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) TPE interval (resting) ( 32386560) Waist circumference adjusted for body mass index ( 28552196) White blood cell count ( 32888494)	Birth weight ( 31043758) Hematocrit ( 32888494) Offspring birth weight ( 31043758) Polycystic ovary syndrome ( 26284813)
Interacting Genes		8 interacting genes: ABCC2 ADSS1 ARNTL CDKN2A FANCA FANCC KHDRBS1 OAZ3	54 interacting genes: APC AZIN1 BMPR1A BUB1 CAPN10 CCNA2 CCND1 CDK1 CTBP1 DLC1 DNAJB1 EGFR FANCA FANCD2 FANCE FANCF FANCG FBXW7 GSTP1 HSP90AA1 HSP90B1 HSPA1A HSPA4 HSPA8 IK KRAS KRT1 MEOX2 MLH3 MT-ATP6 MUTYH NRAS PDGFRL PIK3CA PMS2 POR PRDX3 PRPF31 PTPN12 PTPRJ RB1 RPL18 RPS3A SMAD4 SPTA1 SPTAN1 SRC STAT1 STMN1 STMN2 TCERG1 TGFBR2 USP14 ZBTB32
Entrez ID		51582	2176
HPRD ID		07443	01967
Ensembl ID		ENSG00000155096	ENSG00000158169
Uniprot IDs		A0A024R9C7 B3KTF6 O14977	A0A024R9N2 A0A087WW44 B4E3W2 Q00597
PDB IDs		4ZGZ
Enriched GO Terms of Interacting Partners?
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