ETV7 and L3MBTL1

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro)

		ETV7	L3MBTL1
Description		ETS variant transcription factor 7	L3MBTL histone methyl-lysine binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Chromatin Condensed Chromosome Nucleus Nucleoplasm Nucleolus Plasma Membrane
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	Chromatin Binding Protein Binding Zinc Ion Binding Nucleosome Binding Nucleosomal Histone Binding SAM Domain Binding Methylated Histone Binding Histone Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Animal Organ Morphogenesis Cell Differentiation	Chromatin Organization Regulation Of Mitotic Nuclear Division Hemopoiesis Regulation Of Megakaryocyte Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Cell Cycle Regulation Of Signal Transduction By P53 Class Mediator
Pathways			Regulation of TP53 Activity through Methylation
Drugs			2-(N-morpholino)ethanesulfonic acid
Diseases
GWAS		Mean platelet volume ( 27863252) Multiple sclerosis ( 31604244) Platelet count ( 27863252) Rheumatoid arthritis ( 30423114) Systemic lupus erythematosus ( 28714469) White blood cell count ( 29403010)	Antibody level in response to infection ( 25758998) Daytime sleep phenotypes ( 27126917)
Interacting Genes		5 interacting genes: IRF4 L3MBTL1 LRPAP1 VTN WT1	7 interacting genes: CBX3 ETV6 ETV7 H1-5 H4-16 RB1 SETD7
Entrez ID		51513	26013
HPRD ID		16095	16387
Ensembl ID		ENSG00000010030	ENSG00000185513
Uniprot IDs		Q9Y603	Q9Y468
PDB IDs			1OYX 1OZ2 1OZ3 2PQW 2RHI 2RHU 2RHX 2RHY 2RHZ 2RI2 2RI3 2RI5 2RJC 2RJD 2RJE 2RJF 3OQ5 3P8H 3UWN 6BYB
Enriched GO Terms of Interacting Partners?
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