L3MBTL1 and ETV7

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro)

		L3MBTL1	ETV7
Description		L3MBTL histone methyl-lysine binding protein 1	ETS variant transcription factor 7
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Condensed Chromosome Nucleus Nucleoplasm Nucleolus Plasma Membrane	Chromatin Nucleus Nucleoplasm
	Molecular Function	Chromatin Binding Protein Binding Zinc Ion Binding Nucleosome Binding Nucleosomal Histone Binding SAM Domain Binding Methylated Histone Binding Histone Binding Identical Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Chromatin Organization Regulation Of Mitotic Nuclear Division Hemopoiesis Regulation Of Megakaryocyte Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Cell Cycle Regulation Of Signal Transduction By P53 Class Mediator	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Animal Organ Morphogenesis Cell Differentiation
Pathways		Regulation of TP53 Activity through Methylation
Drugs		2-(N-morpholino)ethanesulfonic acid
Diseases
GWAS		Antibody level in response to infection ( 25758998) Daytime sleep phenotypes ( 27126917)	Mean platelet volume ( 27863252) Multiple sclerosis ( 31604244) Platelet count ( 27863252) Rheumatoid arthritis ( 30423114) Systemic lupus erythematosus ( 28714469) White blood cell count ( 29403010)
Interacting Genes		7 interacting genes: CBX3 ETV6 ETV7 H1-5 H4-16 RB1 SETD7	5 interacting genes: IRF4 L3MBTL1 LRPAP1 VTN WT1
Entrez ID		26013	51513
HPRD ID		16387	16095
Ensembl ID		ENSG00000185513	ENSG00000010030
Uniprot IDs		Q9Y468	Q9Y603
PDB IDs		1OYX 1OZ2 1OZ3 2PQW 2RHI 2RHU 2RHX 2RHY 2RHZ 2RI2 2RI3 2RI5 2RJC 2RJD 2RJE 2RJF 3OQ5 3P8H 3UWN 6BYB
Enriched GO Terms of Interacting Partners?
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