CHMP5 and MITD1

Data Source:
BioGRID (two hybrid)

		CHMP5	MITD1
Description		charged multivesicular body protein 5	microtubule interacting and trafficking domain containing 1
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GO Annotations	Cellular Component	Nucleus Multivesicular Body Cytosol Endosome Membrane Extracellular Exosome	Extrinsic Component Of Membrane Midbody Late Endosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Protein Binding Cadherin Binding	Protein Binding Protein Domain Specific Binding Phosphatidylinositol Binding Identical Protein Binding
	Biological Process	Regulation Of Receptor Recycling Vesicle Budding From Membrane Nucleus Organization Lysosome Organization Mitotic Metaphase Plate Congression Endosome To Lysosome Transport Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Viral Life Cycle Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Midbody Abscission Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly ESCRT III Complex Disassembly	Mitotic Cytokinesis Negative Regulation Of Protein Binding Viral Budding Via Host ESCRT Complex Midbody Abscission Multivesicular Body Sorting Pathway
Pathways		Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Erectile dysfunction and prostate cancer treatment ( 20932654)	Bipolar disorder ( 21926972)
Interacting Genes		16 interacting genes: APPBP2 CHMP1B CHMP4A CHMP4B GTF3A MITD1 NOD2 PDCD10 RPL38 SMARCA4 STAMBP URGCP VPS4B VTA1 ZNF142 ZNF91	15 interacting genes: ATF7 CARD10 CHMP1A CHMP1B CHMP2A CHMP5 GPHN KANK2 MCPH1 NTAQ1 RTN3 TRIM14 TTC33 ZFYVE19 ZNF655
Entrez ID		51510	129531
HPRD ID		15408	14044
Ensembl ID		ENSG00000086065	ENSG00000158411
Uniprot IDs		Q9NZZ3	Q8WV92
PDB IDs		2LXM 3ULY 3UM0 3UM1 3UM2 4TXR	2YMB 4A5X 4A5Z
Enriched GO Terms of Interacting Partners?
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