CHMP5 and GTF3A

Data Source:
HPRD (two hybrid)

		CHMP5	GTF3A
Description		charged multivesicular body protein 5	general transcription factor IIIA
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Multivesicular Body Cytosol Endosome Membrane Extracellular Exosome	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Cadherin Binding	DNA Binding 5S RRNA Binding Metal Ion Binding
	Biological Process	Regulation Of Receptor Recycling Vesicle Budding From Membrane Nucleus Organization Lysosome Organization Mitotic Metaphase Plate Congression Endosome To Lysosome Transport Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Viral Life Cycle Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Midbody Abscission Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly ESCRT III Complex Disassembly	Transcription By RNA Polymerase III RRNA Transcription Ribosomal Large Subunit Biogenesis
Pathways		Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)	RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Erectile dysfunction and prostate cancer treatment ( 20932654)	Body mass index ( 20935630) Body size at age 10 ( 32376654) Night sleep phenotypes ( 27126917)
Interacting Genes		16 interacting genes: APPBP2 CHMP1B CHMP4A CHMP4B GTF3A MITD1 NOD2 PDCD10 RPL38 SMARCA4 STAMBP URGCP VPS4B VTA1 ZNF142 ZNF91	4 interacting genes: CHMP5 GTF3C2 OPTN SCYL2
Entrez ID		51510	2971
HPRD ID		15408	02916
Ensembl ID		ENSG00000086065	ENSG00000122034
Uniprot IDs		Q9NZZ3	Q92664
PDB IDs		2LXM 3ULY 3UM0 3UM1 3UM2 4TXR
Enriched GO Terms of Interacting Partners?
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