MITD1 and GPHN

Data Source:
BioGRID (two hybrid)

		MITD1	GPHN
Description		microtubule interacting and trafficking domain containing 1	gephyrin
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GO Annotations	Cellular Component	Extrinsic Component Of Membrane Midbody Late Endosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Postsynaptic Density Dendrite Postsynaptic Membrane Synaptic Membrane Anchored Component Of Synaptic Membrane Postsynaptic Specialization Postsynaptic Specialization Membrane
	Molecular Function	Protein Binding Protein Domain Specific Binding Phosphatidylinositol Binding Identical Protein Binding	Protein Binding ATP Binding Nitrate Reductase Activity Identical Protein Binding Molybdopterin Cofactor Binding Metal Ion Binding Molybdopterin Adenylyltransferase Activity Molybdopterin Molybdotransferase Activity
	Biological Process	Mitotic Cytokinesis Negative Regulation Of Protein Binding Viral Budding Via Host ESCRT Complex Midbody Abscission Multivesicular Body Sorting Pathway	Mo-molybdopterin Cofactor Biosynthetic Process Establishment Of Synaptic Specificity At Neuromuscular Junction Response To Metal Ion Molybdenum Incorporation Into Molybdenum-molybdopterin Complex Molybdopterin Cofactor Biosynthetic Process Glycine Receptor Clustering Gamma-aminobutyric Acid Receptor Clustering Postsynaptic Neurotransmitter Receptor Diffusion Trapping
Pathways			Molybdenum cofactor biosynthesis
Drugs			Formic acid Imidazole Propanoic acid
Diseases			Hyperekplexia
GWAS		Bipolar disorder ( 21926972)	Depression (quantitative trait) ( 23290196) Pneumococcal meningitis ( 31092817) Tandem gait ( 26219847) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		15 interacting genes: ATF7 CARD10 CHMP1A CHMP1B CHMP2A CHMP5 GPHN KANK2 MCPH1 NTAQ1 RTN3 TRIM14 TTC33 ZFYVE19 ZNF655	15 interacting genes: ACADVL ARHGEF9 DYNLL1 DYNLL2 ENAH GABARAP GLRB KHDRBS1 MITD1 MTOR PFN1 PIN1 PSMA1 SPATS1 TUBA4A
Entrez ID		129531	10243
HPRD ID		14044	04893
Ensembl ID		ENSG00000158411	ENSG00000171723
Uniprot IDs		Q8WV92	Q9NQX3
PDB IDs		2YMB 4A5X 4A5Z	1JLJ
Enriched GO Terms of Interacting Partners?
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