EIF3L and EIF3K

Data Source:
HPRD (two hybrid)

		EIF3L	EIF3K
Description		eukaryotic translation initiation factor 3 subunit L	eukaryotic translation initiation factor 3 subunit K
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GO Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex	Nucleus Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex
	Molecular Function	RNA Binding Translation Initiation Factor Activity Protein Binding	Translation Initiation Factor Activity Protein Binding Ribosome Binding
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Viral Translational Termination-reinitiation	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Regulation Of Translational Initiation
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		12 interacting genes: DNM2 EIF3D EIF3E EIF3K ERCC6 HRAS POLR1B PPP1R18 RGS2 RRN3 SMAD2 XRN2	7 interacting genes: CCND3 EIF3C EIF3G EIF3H EIF3J EIF3L SPP1
Entrez ID		51386	27335
HPRD ID		10932	11740
Ensembl ID		ENSG00000100129	ENSG00000178982
Uniprot IDs		Q9Y262	K7EK53 K7ERF1 Q9UBQ5 U3LUI4
PDB IDs		3J8B 3J8C 6FEC 6YBD 6ZMW 6ZON 6ZP4 6ZVJ 7A09	1RZ4 3J8B 3J8C 6FEC 6YBD 6ZMW 6ZON 6ZP4 6ZVJ 7A09
Enriched GO Terms of Interacting Partners?
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