HOOK1 and VPS16

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		HOOK1	VPS16
Description		hook microtubule tethering protein 1	VPS16 core subunit of CORVET and HOPS complexes
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Microtubule HOPS Complex FHF Complex	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Clathrin-coated Vesicle Axon HOPS Complex Late Endosome Membrane Neuronal Cell Body Recycling Endosome
	Molecular Function	Actin Binding Protein Binding Microtubule Binding Identical Protein Binding Dynein Light Intermediate Chain Binding	Actin Binding Protein Binding Actin Filament Binding
	Biological Process	Golgi Organization Endosome Organization Lysosome Organization Multicellular Organism Development Endosome To Lysosome Transport Protein Transport Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Early Endosome To Late Endosome Transport Manchette Assembly	Intracellular Protein Transport Vacuole Organization Endosome To Lysosome Transport Endosomal Transport Vacuole Fusion, Non-autophagic Autophagosome Maturation
Pathways
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)	Lymphocyte percentage of white cells ( 32888494) Metabolite levels ( 23823483)
Interacting Genes		30 interacting genes: AKTIP ANK3 ANKRD23 CDC5L CDK4 CWF19L2 FAM161A FHIP1B HOOK2 HOOK3 LMO2 MEOX2 PIAS2 SYCE1 TBC1D7 TFIP11 USP2 UTP14C VPS16 VPS18 VPS39 VPS41 ZBTB47 ZNF250 ZNF35 ZNF572 ZNF655 ZNF764 ZNF785 ZNF80	17 interacting genes: AKTIP EXOC8 FBXO7 GNG13 HOOK1 HOOK2 HOOK3 MON1B RAB7A RILP STX1A STX7 UVRAG VPS11 VPS18 VPS33A ZNF417
Entrez ID		51361	64601
HPRD ID		07428	12259
Ensembl ID		ENSG00000134709	ENSG00000215305
Uniprot IDs		Q9UJC3	Q9H269
PDB IDs			4BX9
Enriched GO Terms of Interacting Partners?
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