PCYT1A and GYS1

Data Source:
BioGRID (two hybrid)

		PCYT1A	GYS1
Description		phosphate cytidylyltransferase 1, choline, alpha	glycogen synthase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Glycogen Granule	Cytoplasm Cytosol Membrane Inclusion Body
	Molecular Function	Choline-phosphate Cytidylyltransferase Activity Protein Binding Phosphatidylcholine Binding Identical Protein Binding	Glycogen (starch) Synthase Activity Protein Binding Glucose Binding Protein Kinase Binding Glycogen Synthase Activity, Transferring Glucose-1-phosphate
	Biological Process	Phosphatidylcholine Biosynthetic Process CDP-choline Pathway	Glycogen Biosynthetic Process Heart Development
Pathways		Synthesis of PC	Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage disease type XV (GYG1) Glycogen storage disease type 0 (muscle GYS1)
Drugs		Choline Choline salicylate
Diseases			Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS		Mean platelet volume ( 32888494)
Interacting Genes		16 interacting genes: ACTB AGTRAP CASP6 CASP8 FKBP7 GYS1 MAGEA3 MOB1A MOB3C PCYT1B RNF8 SCAMP1 SDCBP SNAPIN TNFRSF10D VKORC1L1	43 interacting genes: AIMP2 APP BEND7 CCDC33 CDCA8 CLVS2 CRX CSNK2A1 EFHC2 FAM228A GSK3B GYG1 GYG2 HOXB6 HOXC8 IHO1 INCA1 KATNBL1 KLF1 KLF4 MAPKAPK5 MEOX1 NDUFB7 NHLRC1 PCYT1A PINX1 PLAGL2 PNMA5 PRKACA RBM48 SNIP1 SORBS3 SUMO2 TFAP2D TLE5 WASHC1 ZBTB33 ZNF212 ZNF326 ZNF474 ZNF552 ZNF620 ZNF774
Entrez ID		5130	2997
HPRD ID		00438	00721
Ensembl ID		ENSG00000161217	ENSG00000104812
Uniprot IDs		B4E322 P49585	P13807
PDB IDs
Enriched GO Terms of Interacting Partners?
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