RNF181 and NPY5R

Data Source:
BioGRID (two hybrid)

		RNF181	NPY5R
Description		ring finger protein 181	neuropeptide Y receptor Y5
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane Neuron Projection Synapse
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Peptide YY Receptor Activity Pancreatic Polypeptide Receptor Activity Neuropeptide Y Receptor Activity
	Biological Process	Protein Ubiquitination Protein Autoubiquitination	Positive Regulation Of Acute Inflammatory Response Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Outflow Tract Morphogenesis Cardiac Left Ventricle Morphogenesis G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Chemical Synaptic Transmission Aging Negative Regulation Of Glutamate Secretion Negative Regulation Of Synaptic Transmission, GABAergic Eating Behavior Negative Regulation Of Apoptotic Process Positive Regulation Of Smooth Muscle Cell Proliferation Generation Of Ovulation Cycle Rhythm Positive Regulation Of ERK1 And ERK2 Cascade
Pathways		E3 ubiquitin ligases ubiquitinate target proteins	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs			Peptide YY (3-36)
Diseases
GWAS		Prostate cancer ( 21743467)
Interacting Genes		22 interacting genes: BCL10 BIRC2 BTG1 CARD11 CLK4 MRPS6 NPY5R PEG10 RBCK1 TRIM24 TRIM8 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2N UBE2U VPS11 ZMYND10	4 interacting genes: NPY NUPR1 PYY RNF181
Entrez ID		51255	4889
HPRD ID		14236	03591
Ensembl ID		ENSG00000168894	ENSG00000164129
Uniprot IDs		Q9P0P0	Q15761
PDB IDs			2HE6
Enriched GO Terms of Interacting Partners?
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