NPY5R and PYY

Data Source:
HPRD (in vivo)

		NPY5R	PYY
Description		neuropeptide Y receptor Y5	peptide YY
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane Neuron Projection Synapse	Extracellular Region Extracellular Space
	Molecular Function	Peptide YY Receptor Activity Pancreatic Polypeptide Receptor Activity Neuropeptide Y Receptor Activity	G Protein-coupled Receptor Binding Hormone Activity Neuropeptide Hormone Activity Protein Binding Neuropeptide Y Receptor Binding
	Biological Process	Positive Regulation Of Acute Inflammatory Response Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Outflow Tract Morphogenesis Cardiac Left Ventricle Morphogenesis G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Chemical Synaptic Transmission Aging Negative Regulation Of Glutamate Secretion Negative Regulation Of Synaptic Transmission, GABAergic Eating Behavior Negative Regulation Of Apoptotic Process Positive Regulation Of Smooth Muscle Cell Proliferation Generation Of Ovulation Cycle Rhythm Positive Regulation Of ERK1 And ERK2 Cascade	G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Feeding Behavior Intestinal Epithelial Cell Differentiation
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs		Peptide YY (3-36)
Diseases
GWAS			Blood protein levels ( 30072576) Diverticular disease ( 30177863) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Pulse pressure ( 28135244) Response to taxane treatment (placlitaxel) ( 23006423) Triglyceride levels ( 32203549)
Interacting Genes		4 interacting genes: NPY NUPR1 PYY RNF181	6 interacting genes: MEP1B NPY1R NPY2R NPY4R NPY5R SGTA
Entrez ID		4889	5697
HPRD ID		03591	02869
Ensembl ID		ENSG00000164129	ENSG00000131096
Uniprot IDs		Q15761	P10082
PDB IDs		2HE6	2DEZ 2DF0 2L60 2NA5
Enriched GO Terms of Interacting Partners?
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