NPY5R and NPY

Data Source:
HPRD (in vivo)

		NPY5R	NPY
Description		neuropeptide Y receptor Y5	neuropeptide Y
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane Neuron Projection Synapse	Extracellular Region Extracellular Space Golgi Apparatus Synapse Neuronal Dense Core Vesicle
	Molecular Function	Peptide YY Receptor Activity Pancreatic Polypeptide Receptor Activity Neuropeptide Y Receptor Activity	G Protein-coupled Receptor Binding G Protein-coupled Receptor Activity Signaling Receptor Binding Hormone Activity Neuropeptide Hormone Activity Calcium Channel Regulator Activity Protein Binding Neuropeptide Y Receptor Binding
	Biological Process	Positive Regulation Of Acute Inflammatory Response Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Outflow Tract Morphogenesis Cardiac Left Ventricle Morphogenesis G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Chemical Synaptic Transmission Aging Negative Regulation Of Glutamate Secretion Negative Regulation Of Synaptic Transmission, GABAergic Eating Behavior Negative Regulation Of Apoptotic Process Positive Regulation Of Smooth Muscle Cell Proliferation Generation Of Ovulation Cycle Rhythm Positive Regulation Of ERK1 And ERK2 Cascade	G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Chemical Synaptic Transmission Feeding Behavior Regulation Of Blood Pressure Adult Feeding Behavior Central Nervous System Neuron Development Cerebral Cortex Development Neuron Projection Development Positive Regulation Of Appetite Intestinal Epithelial Cell Differentiation
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	Peptide ligand-binding receptors G alpha (i) signalling events FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
Drugs		Peptide YY (3-36)	Phentermine 2-aminoisobutyric acid L-tyrosinamide
Diseases
GWAS			Adult body size ( 32376654) Aggressive periodontitis (sex interaction) ( 25256105) Body size at age 10 ( 32376654) Chronotype ( 30696823) Morning person ( 30696823) Periodontitis ( 23459936) Vitamin D levels ( 25208829)
Interacting Genes		4 interacting genes: NPY NUPR1 PYY RNF181	16 interacting genes: ATP12A BAG6 GHRL MC4R MEP1A MEP1B NPFF NPFFR2 NPY1R NPY2R NPY4R NPY5R NR1H2 PMCH UBQLN1 UBQLN2
Entrez ID		4889	4852
HPRD ID		03591	01214
Ensembl ID		ENSG00000164129	ENSG00000122585
Uniprot IDs		Q15761	A4D158 P01303
PDB IDs		2HE6	1QFA 1RON
Enriched GO Terms of Interacting Partners?
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